Document Detail


Use of ultrasound in antenatal diagnosis of large-for-gestational age infants in diabetic gravid patients.
MedLine Citation:
PMID:  3887925     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Near-term ultrasonograms of 44 diabetic gravid patients and 47 nondiabetic gravid patients were retrospectively analyzed. The mean values of abdominal diameter to femur length ratios and abdominal diameter to biparietal diameter ratios in diabetic gravid patients with large-for-gestational age fetuses were significantly different from those values in diabetic patients with appropriate-for-gestational age fetuses and in nondiabetic patients. Glycosylated hemoglobin values were above 7.4% (mean +/- 2 SD) in 79% of diabetic patients with large-for-gestational age infants and abdominal diameter to femur length ratio exceeding 1.385. Glycosylated hemoglobin values were less than or equal to 7.4% in 69% of diabetic gravid patients with appropriate-for-gestational age fetuses and abdominal diameter to femur length ratio less than 1.385. These findings suggest that large-for-gestational age infants have a different growth characteristic with a disproportionate enlargement of the abdomen. This possibly results from a long period of elevated levels of maternal plasma glucose (as shown by elevated values of glycosylated hemoglobin).
Authors:
L A Bracero; L V Baxi; H R Rey; M N Yeh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  152     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1985 May 
Date Detail:
Created Date:  1985-06-06     Completed Date:  1985-06-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  43-7     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Blood Glucose / analysis
Embryonic and Fetal Development*
Female
Fetus / anatomy & histology
Gestational Age*
Hemoglobin A, Glycosylated / analysis
Humans
Pregnancy
Pregnancy in Diabetics* / blood
Retrospective Studies
Ultrasonography*
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Hemoglobin A, Glycosylated

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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