Document Detail

Use of topical benzydamine in gynecology.
MedLine Citation:
PMID:  7042126     Owner:  NLM     Status:  MEDLINE    
To evaluate the topical anti-inflammatory activity of benzydamine when used as 0.1% solution for vaginal douche, a double blind, parallel group, randomized clinical trial was carried out on 30 patients with vaginitis following internal radiotherapy for carcinoma of the uterus. The patients were divided into 3 groups, one being treated with 0.1% benzydamine plus tricetol as preservative, one with 0.1% benzydamine alone, and one with placebo. Treatment began 12-24 hours after radiotherapy. Benzydamine was found to be significantly superior to placebo in its overall topical anti-inflammatory activity both after 5 and 15 days of treatment. Tricetol did not interfere with the therapeutic effect of benzydamine.
G Bentivoglio; F Diani
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Clinical and experimental obstetrics & gynecology     Volume:  8     ISSN:  0390-6663     ISO Abbreviation:  Clin Exp Obstet Gynecol     Publication Date:  1981  
Date Detail:
Created Date:  1982-07-08     Completed Date:  1982-07-08     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7802110     Medline TA:  Clin Exp Obstet Gynecol     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  103-10     Citation Subset:  IM    
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MeSH Terms
Administration, Topical
Benzydamine / administration & dosage*
Clinical Trials as Topic
Double-Blind Method
Middle Aged
Pyrazoles / administration & dosage*
Random Allocation
Uterine Neoplasms / radiotherapy
Vaginitis / drug therapy*,  etiology
Reg. No./Substance:
0/Pyrazoles; 642-72-8/Benzydamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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