Document Detail


Use of terbutaline in the treatment of complete heart block in the fetus.
MedLine Citation:
PMID:  11813927     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Between 1989 and 2000, 21 fetuses were diagnosed with complete atrioventricular block. Seven women with fetal ventricular rates of less than 60 were given oral terbutaline, and 6 of these had an initial increase in the fetal ventricular rate. Four fetuses (57%) maintained an increased average rate of 60 beats per minute and survived. Two fetuses returned to rates below 55 and died. The final fetus, with hypertrophic cardiomyopathy, was unresponsive. Terbutaline, therefore, is initially effective in raising the fetal ventricular rate, but this effect may be transient.
Authors:
B V Robinson; J A Ettedgui; F S Sherman
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Cardiology in the young     Volume:  11     ISSN:  1047-9511     ISO Abbreviation:  Cardiol Young     Publication Date:  2001 Nov 
Date Detail:
Created Date:  2002-01-29     Completed Date:  2002-07-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9200019     Medline TA:  Cardiol Young     Country:  England    
Other Details:
Languages:  eng     Pagination:  683-6     Citation Subset:  IM    
Affiliation:
University of North Carolina at Chapel Hill, USA. brobins@med.unc.edu
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MeSH Terms
Descriptor/Qualifier:
Adrenergic beta-Agonists / therapeutic use*
Dose-Response Relationship, Drug
Echocardiography
Female
Fetal Diseases / diagnosis,  drug therapy*,  mortality
Fetal Heart / abnormalities*,  ultrasonography
Gestational Age
Heart Block / diagnosis,  drug therapy*,  mortality
Heart Rate / drug effects,  physiology
Humans
Hydrops Fetalis / etiology,  mortality
Infant Welfare
Infant, Newborn
Male
Noonan Syndrome / drug therapy,  etiology,  mortality
Pennsylvania
Pregnancy
Pregnancy Complications, Cardiovascular / diagnosis,  drug therapy
Respiratory Distress Syndrome, Newborn / drug therapy,  etiology,  mortality
Survival Analysis
Terbutaline / therapeutic use*
Treatment Outcome
Women's Health
Chemical
Reg. No./Substance:
0/Adrenergic beta-Agonists; 23031-25-6/Terbutaline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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