Document Detail

Use of technetium-labeled red blood cell scintigraphy in the detection and management of gastrointestinal hemorrhage.
MedLine Citation:
PMID:  1925969     Owner:  NLM     Status:  MEDLINE    
The effectiveness of technetium 99m-labeled red blood cell scintigraphy in localizing hemorrhage, directing surgical intervention, and screening patients for arteriography was determined in 103 patients. The radionuclide scan result was compared to the bleeding site determined by arteriography, endoscopy, or surgery. Eighty-five patients had a bleeding site identified; 18 patients did not and were excluded. Thirty-one scans were performed in 29 patients for upper gastrointestinal hemorrhage. Five positive scans incorrectly localized an upper gastrointestinal bleeding site, although two scans localized the site, for a scan sensitivity of 8%. Fifty-nine scans were performed in 56 patients with lower gastrointestinal bleeding. Fifteen scans were positive, three incorrectly localizing the hemorrhage. Seventy-four percent of the patients with lower gastrointestinal hemorrhage documented by arteriography, endoscopy, or surgery had negative scans for bleeding. The radionuclide scan sensitivity for lower gastrointestinal bleeding was 23%. Surgery was required in 18 patients for bleeding, 11 of whom had negative scans for bleeding. In seven surgical patients with positive scans, in no instance did the scan direct the surgical intervention. Eighteen patients underwent scintigraphy and arteriography; nearly one half of the patients with negative scans for bleeding had positive localizing arteriograms, although almost one half of the patients with positive scans for bleeding had negative arteriograms. Scintigraphy failed to localize hemorrhage in 85% of the patients. Technetium 99m-labeled red blood cell scintigraphy did not direct surgical intervention, nor did it adequately screen patients for arteriography.
G R Voeller; G Bunch; L G Britt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Surgery     Volume:  110     ISSN:  0039-6060     ISO Abbreviation:  Surgery     Publication Date:  1991 Oct 
Date Detail:
Created Date:  1991-10-30     Completed Date:  1991-10-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417347     Medline TA:  Surgery     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  799-804     Citation Subset:  AIM; IM    
Department of Surgery, University of Tennessee, Memphis 38163.
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MeSH Terms
Aged, 80 and over
Erythrocytes / radionuclide imaging*
Gastrointestinal Hemorrhage / diagnosis,  radionuclide imaging*,  surgery
Middle Aged
Sensitivity and Specificity
Technetium / diagnostic use*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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