| Use of single MRI and 18F-FDG PET-CT scans in both diagnosis and radiotherapy treatment planning in patients with head and neck cancer: advantage on target volume and critical organ delineation. | |
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MedLine Citation:
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PMID: 19072998 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The use of a single MRI and 18F-fluoro deoxyglucose positron emission tomography-CT (18F-FDG PET-CT) was evaluated, both in diagnostic procedure and radiotherapy planning, in patients with head and neck cancer. METHODS: Thirty-five patients with nasopharyngeal and oropharyngeal tumors were studied. The MRI and 18F-FDG PET-CT were used for both diagnostic work-up and gross tumor volume and critical structure delineation. The interobserver variation (IOV) of volumes determined on MRI and CT by a radiotherapist and by a radiologist were compared as well as their impact on dose distribution. RESULTS: The CT-MRI decreased the IOV of parotid glands in 12 of 35 and target volume in 15 of 35 patients. The use of 18F-FDG PET-CT changed the treatment design in 6 of 21 patients. CONCLUSIONS: Diagnostic imaging performed in the treatment position can improve the accuracy of radiotherapy planning in case of intracranial tumor extension, heavy dental work, or contraindication for contrast-enhanced CT, but not in the absence of these conditions. |
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Authors:
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Miriam Gardner; Philippe Halimi; Danielle Valinta; Marie-Madeleine Plantet; Jean-Louis Alberini; Myriam Wartski; Alain Banal; Stephane Hans; Jean-Louis Floiras; Martin Housset; Alain Labib |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Head & neck Volume: 31 ISSN: 1097-0347 ISO Abbreviation: Head Neck Publication Date: 2009 Apr |
Date Detail:
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Created Date: 2009-03-19 Completed Date: 2009-07-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8902541 Medline TA: Head Neck Country: United States |
Other Details:
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Languages: eng Pagination: 461-7 Citation Subset: IM |
Affiliation:
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Service de Radiothérapie, Centre René Huguenin, Saint-Cloud, France. gardner@crhl.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Carcinoma / diagnosis, radiotherapy* Carcinoma, Squamous Cell / diagnosis, radiotherapy Female Fluorodeoxyglucose F18 / diagnostic use* Humans Magnetic Resonance Imaging* Male Middle Aged Nasopharyngeal Neoplasms / diagnosis, radiotherapy* Oropharyngeal Neoplasms / diagnosis, radiotherapy* Parotid Gland / pathology, radiation effects, radiography Radiopharmaceuticals / diagnostic use* Radiotherapy Dosage Radiotherapy Planning, Computer-Assisted* Tomography, X-Ray Computed* |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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