Document Detail

Use of serum progesterone levels as an early, indirect evaluation of pregnancy in the timed pregnant domestic cat.
MedLine Citation:
PMID:  1849585     Owner:  NLM     Status:  MEDLINE    
There has been much research studying the effect of homotypic embryonic neural tissue transplantation in the central nervous system of rats and cats, with promising results. The benefits of transplantation are dependent upon the appropriate aged donor. Therefore, it is critical that the exact age of the embryonic tissue be known. For this reason we have developed a method of determining, indirectly, the pregnancy status and embryonic age in the domestic cat (Felis catus) using serum progesterone levels. Serum progesterone levels were monitored in 16 domestic cats during 26 breeding trials. Blood samples were taken prior to and 6 days after natural breeding to determine if ovulation had occurred, indirectly indicating pregnancy status. By knowing the exact date bred and if it resulted in pregnancy, an accurate embryonic age was calculated. A day 6 post-breeding serum progesterone concentration of less than 5.0 ng/ml was considered a negative indication of pregnancy, greater than 5.0 ng/ml a positive indication of pregnancy. Pregnancy was confirmed by abdominal palpation 21 to 26 days after breeding. Serum progesterone levels taken on the sixth day after observed breeding provide an accurate, indirect evaluation of pregnancy in the timed pregnant domestic cat (81%, p = 0.003).
J G Hammer; D R Howland
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Laboratory animal science     Volume:  41     ISSN:  0023-6764     ISO Abbreviation:  Lab. Anim. Sci.     Publication Date:  1991 Jan 
Date Detail:
Created Date:  1991-05-13     Completed Date:  1991-05-13     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  1266503     Medline TA:  Lab Anim Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  42-5     Citation Subset:  IM    
Medical College of Pennsylvania, Philadelphia 19129.
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MeSH Terms
Animals, Domestic
Evaluation Studies as Topic
False Negative Reactions
False Positive Reactions
Pregnancy Tests / methods,  veterinary*
Pregnancy, Animal / blood*
Progesterone / blood*
Time Factors
Grant Support
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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