Document Detail


Use of serum gamma glutamyl transpeptidase to differentiate between extrahepatic biliary atresia and neonatal hepatitis.
MedLine Citation:
PMID:  2571663     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The differentiation between extrahepatic biliary atresia (EHBA) and neonatal hepatitis (NH) was studied in 53 Thai infants (39 males, 14 females) with obstructive cholangiopathy at the Department of Pediatrics, Siriraj hospital. Prevalence of EHBA was 25 per cent (13 of 15) overall. A higher prevalence of EHBA was found in females (8 of 13) while a higher prevalence of NH occurred in males (34 of 40). No difference was demonstrated in serum conjugated and total bilirubin, SGOT or alkaline phosphatase between EHBA and NH groups. The EHBA group had a significantly higher mean serum GGTP (184 +/- 77 IU/L) than the NH group (58 +/- 40 IU/L). The diagnostic usefulness of GGTP was confirmed, but variation in laboratory measurements could limit its generalizability.
Authors:
C Vajaradul; N Vanprapar; T Chuenmeechow; S Ongajyooth
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  72     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  1989 Jul 
Date Detail:
Created Date:  1989-11-21     Completed Date:  1989-11-21     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  THAILAND    
Other Details:
Languages:  eng     Pagination:  395-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Biliary Atresia / diagnosis*
Clinical Enzyme Tests*
Diagnosis, Differential
Female
Hepatitis / diagnosis*
Humans
Infant
Infant, Newborn
Male
Sex Factors
gamma-Glutamyltransferase / blood*,  metabolism
Chemical
Reg. No./Substance:
EC 2.3.2.2/gamma-Glutamyltransferase

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