Document Detail


Use of a self-designed bladder controller for restoring bladder function in paraplegic dogs.
MedLine Citation:
PMID:  12857509     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate the results of a self-designed bladder controller for restoring micturition function in paraplegic dogs. METHODS: The spinal cords of 4 dogs were transected above the cone. Electrodes were implanted in S2 bilaterally and connected to the subcutaneous receivers for external activation. Microsurgical technique was employed to perform dorsal rhizotomy of S1-3 intradurally. The dogs were stimulated daily to observe micturition. Urodynamic testing and vesicography were performed. RESULTS: All the dogs acquired micturition under the control of electric stimulation, with urine volume 80-140 ml per time. The mode of micturition was post-stimulus voiding. Vesicography revealed that the bladder was filled well and the bladder neck was open in the micturition course of electric stimulation. Residual urine volume was 15-20 ml. Urodynamic testing found that the bladder pressure and intraurethral pressure increased simultaneously, but when the intraurethral pressure was greater than the bladder pressure, no micturition occurred. The pressure decreased to baseline rapidly and the bladder pressure decreased slowly between two bursts. Micturition occurred when the bladder pressure was greater than the intraurethral pressure. CONCLUSIONS: The self-designed bladder controller together with a sacral deafferentation procedure can restore micturition function of paraplegic dogs.
Authors:
Shi-bo Wang; Chun-lin Hou; Ying-min Diao; Ai-min Chen; Shi-min Zhang; Bo Lei; Cheng-hui Yin; Wei Zhang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chinese journal of traumatology = Zhonghua chuang shang za zhi / Chinese Medical Association     Volume:  6     ISSN:  1008-1275     ISO Abbreviation:  Chin. J. Traumatol.     Publication Date:  2003 Aug 
Date Detail:
Created Date:  2003-07-14     Completed Date:  2003-10-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100886162     Medline TA:  Chin J Traumatol     Country:  China    
Other Details:
Languages:  eng     Pagination:  195-8     Citation Subset:  IM    
Affiliation:
Department of Orthopaedics, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China. Wangshibo118@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Animals
Dogs
Electric Stimulation Therapy*
Male
Paraplegia / physiopathology*
Urinary Bladder / physiopathology*,  radiography
Urodynamics

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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