Document Detail


Use of repetitive transcranial magnetic stimulation in pain relief.
MedLine Citation:
PMID:  18457536     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Repetitive transcranial magnetic stimulation (rTMS) of the cerebral cortex is a noninvasive strategy that could have the potential to relieve severe chronic pain, at least partially and transiently. The most studied target of stimulation is the precentral (motor) cortex, but other targets, such as the dorsolateral prefrontal cortex or the parietal cortex, could be of interest. Analgesic effects have been produced by rTMS in patients with neuropathic pain, fibromyalgia or visceral pain. Therapeutic applications of rTMS in pain syndromes are limited by the short duration of the induced effects, but prolonged pain relief can be obtained by performing rTMS sessions every day for several weeks. In patients who respond to rTMS but relapse, surgical implantation of epidural cortical electrodes and a pulse generator can be proposed to make clinical effects more permanent. The rate of improvement produced by rTMS may be predictive for the outcome of the implanted procedure. The place of rTMS as a therapeutic tool in the management of chronic pain remains to be determined.
Authors:
Jean-Pascal Lefaucheur
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Expert review of neurotherapeutics     Volume:  8     ISSN:  1744-8360     ISO Abbreviation:  Expert Rev Neurother     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-05-06     Completed Date:  2008-06-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101129944     Medline TA:  Expert Rev Neurother     Country:  England    
Other Details:
Languages:  eng     Pagination:  799-808     Citation Subset:  IM    
Affiliation:
Service de Physiologie, Explorations Fonctionnelles, Hôpital Henri Mondor, Assistance Publique-Hôpitaux de Paris, 51, Avenue de Lattre de Tassigny, 94010 Créteil, France. jean-pascal.lefaucheur@hmn.aphp.fr
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MeSH Terms
Descriptor/Qualifier:
Clinical Trials as Topic / trends*
Humans
Pain / prevention & control*
Transcranial Magnetic Stimulation / methods*,  trends*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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