Document Detail


Use of recombinant activated factor VII in massive obstetric haemorrhage.
MedLine Citation:
PMID:  17126006     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Massive obstetric haemorrhage is a life-threatening emergency that remains a major cause of maternal mortality. Conventional management is aimed at optimising uterine tone, replacing circulating volume and blood products, and surgery to achieve haemostasis. Recently there have been numerous reports of the (unlicensed) use of recombinant activated factor VII in the management of major obstetric haemorrhage. We report our experience of using it in the treatment of major post-partum haemorrhage in four previously healthy parturients. The published reports of recombinant activated factor VII use in post-partum haemorrhage (unrelated to pre-existing coagulopathies) are compared.
Authors:
J Haynes; M Laffan; F Plaat
Related Documents :
13116026 - The maternal welfare committee of san diego; an educational function to save the lives ...
12521696 - Dying undelivered.
15715846 - Maternal genetic effects set the potential for evolution in a free-living vertebrate po...
25155966 - Enteral granulocyte-colony stimulating factor and erythropoietin early in life improve...
9160726 - Unusual ampullary sperm crypts, and behavior and role of the cumulus oophorus, in the o...
11136786 - Outbreak of necrotizing enterocolitis associated with enterobacter sakazakii in powdere...
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2006-11-27
Journal Detail:
Title:  International journal of obstetric anesthesia     Volume:  16     ISSN:  0959-289X     ISO Abbreviation:  Int J Obstet Anesth     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2006-12-20     Completed Date:  2007-04-23     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9200430     Medline TA:  Int J Obstet Anesth     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  40-9     Citation Subset:  IM    
Affiliation:
Obstetric Anaesthesia Department, Queen Charlotte's and Chelsea Hospital, and Department of Haematology, Hammersmith Hospital, London, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Blood Coagulation Disorders / etiology,  therapy
Cesarean Section / methods
Coagulants / therapeutic use*
Factor VII / therapeutic use*
Factor VIIa
Female
Humans
Leiomyoma / complications
Postpartum Hemorrhage / therapy*
Pregnancy
Recombinant Proteins / therapeutic use
Uterine Neoplasms / complications
Chemical
Reg. No./Substance:
0/Coagulants; 0/Recombinant Proteins; 0/recombinant FVIIa; 9001-25-6/Factor VII; EC 3.4.21.21/Factor VIIa
Comments/Corrections
Comment In:
Int J Obstet Anesth. 2007 Jul;16(3):299-300; author reply 300   [PMID:  17509865 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Post dural puncture headache in obstetric patients: experience from a West African teaching hospital...
Next Document:  Anesthesia for cesarean section in a patient with Holt-Oram syndrome.