| Use of radiotherapy to treat life-threatening Kasabach-Merritt syndrome. | |
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MedLine Citation:
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PMID: 19453533 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Kasabach-Merritt syndrome involves thrombocytopenia, which is usually severe, in association with haemangiomata. We describe two newborn infants who developed life-threatening Kasabach-Merritt syndrome but who were successfully treated. Both had failed to respond adequately to corticosteroids and alpha-interferon. They subsequently received emergency radiotherapy. Both patients had an improvement in their platelet counts. The first infant's haemangioma gradually faded during the first 3 years of life, whereas the second infant's haemangioma had resolved 2 months after radiotherapy. No significant late effects of the radiotherapy have been noted at the 8 and 5 years follow up respectively. Radiotherapy remains an important treatment method in Kasabach-Merritt syndrome when patients fail to respond to other treatments. |
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Authors:
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E Leong; S Bydder |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of medical imaging and radiation oncology Volume: 53 ISSN: 1754-9485 ISO Abbreviation: - Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-05-20 Completed Date: 2009-08-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101469340 Medline TA: J Med Imaging Radiat Oncol Country: Australia |
Other Details:
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Languages: eng Pagination: 87-91 Citation Subset: IM |
Affiliation:
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Departments of Radiation Oncology, Sir Charles Gairdner Hospital, Western Australia, Australia. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Catastrophic Illness
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therapy Hemangioma / congenital, diagnosis*, radiotherapy* Humans Infant, Newborn Male Syndrome Thrombocytopenia, Neonatal Alloimmune / diagnosis*, radiotherapy* Treatment Outcome |
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