| Use of propranolol to control rate-pressure product during cardiac anesthesia. | |
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MedLine Citation:
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PMID: 7027826 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The use of propranolol to control heart rate (HR), systolic pressure, and rate-pressure product (RPP) during laryngoscopy and sternotomy was studied in 21 patients, New York Heart Association functional Classes 1 and 2, scheduled for coronary artery bypass graft surgery. All patients were anesthetized in an identical fashion, but the treatment group (N = 13) received propranolol, 0.5 to 1 mg IV, 4 minutes before laryngoscopy and again, in most cases, before skin incision. Patients not given propranolol (N = 8) showed a clinically and statistically significant increase in HR and RPP, whereas HR and RPP remained essentially unchanged from the preanesthetic period in patients given propranolol. |
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Authors:
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A M Safwat; J A Reitan; G R Misle; E J Hurley |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Anesthesia and analgesia Volume: 60 ISSN: 0003-2999 ISO Abbreviation: Anesth. Analg. Publication Date: 1981 Oct |
Date Detail:
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Created Date: 1981-12-15 Completed Date: 1981-12-15 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 1310650 Medline TA: Anesth Analg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 732-5 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anesthesia* Blood Pressure / drug effects* Clinical Trials as Topic Coronary Artery Bypass* Female Heart Rate / drug effects* Humans Laryngoscopy Male Middle Aged Propranolol / therapeutic use* Random Allocation |
| Chemical | |
Reg. No./Substance:
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525-66-6/Propranolol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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