Document Detail

Use of a predictor for total body potassium content: application to nutrition and hypertension.
MedLine Citation:
PMID:  3183533     Owner:  NLM     Status:  MEDLINE    
Total body potassium (TBK), measured at different institutions, has no reference standard for comparison. A useful reference formula, however, based on body size and age, has been derived at the Brookhaven National Laboratory. This formula was used to help calibrate a simple whole body counter for measuring total potassium and applied to nutrition and hypertension studies. A sodium iodide detector was used for counting gamma rays emitted by potassium-40 to estimate TBK. The mean ratio (+/- S.D.) of adjusted TBK measurements to predicted values was 1.002 +/- 0.047. The ratio of lean body mass estimated by the TBK measurement to that derived from skin fold thickness was 1.069 +/- 0.056. In hypertensives on low dose thiazide, the ratio of TBK measurements to predicted values was 0.994 +/- 0.052. Thus, our TBK measurements were adjusted in close agreement with a predictor formula, provided higher estimates of lean body mass than did skin fold thickness, and showed no change in thiazide treated hypertensives.
K Goldenberg; F K Tomlinson
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of medicine     Volume:  19     ISSN:  0025-7850     ISO Abbreviation:  J Med     Publication Date:  1988  
Date Detail:
Created Date:  1988-12-12     Completed Date:  1988-12-12     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7505566     Medline TA:  J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  215-27     Citation Subset:  IM    
Department of Medicine, Wright State University, Dayton, OH 45435.
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MeSH Terms
Body Composition*
Body Constitution
Hypertension / metabolism*
Middle Aged
Nutritional Physiological Phenomena*
Potassium / analysis*
Potassium Radioisotopes / diagnostic use
Reference Standards
Skinfold Thickness
Grant Support
5 S07 RRO 5794-08/RR/NCRR NIH HHS
Reg. No./Substance:
0/Potassium Radioisotopes; 7440-09-7/Potassium

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