| Use of povidone-iodine during the first trimester of pregnancy: a correct practice? | |
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MedLine Citation:
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PMID: 19187379 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Povidone-iodine (PVP-I) has been widely used as an antiseptic agent during invasive procedures for prenatal diagnosis. Women have been reported of thyroid dysfunction after simple exposure to PVP-I. We studied the effect on thyroid function and urinary iodine excretion after a single topical application of PVP-I in 31 women who had a miscarriage during the first trimester of pregnancy. PVP-I is absorbed through the skin and the vaginal mucosa, resulting in a sudden increase in the urinary excretion of iodine and a short-term variation in concentrations of thyroid hormones in maternal serum. This metabolic effect could have consequences for the embryo and the fetus during crucial stages of development. |
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Authors:
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I Velasco; S Naranjo; C López-Pedrera; M J Garriga; E García-Fuentes; F Soriguer |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: BJOG : an international journal of obstetrics and gynaecology Volume: 116 ISSN: 1471-0528 ISO Abbreviation: BJOG Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-02-03 Completed Date: 2009-04-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100935741 Medline TA: BJOG Country: England |
Other Details:
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Languages: eng Pagination: 452-5 Citation Subset: AIM; IM |
Affiliation:
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Servicio de Obstetricia y Ginecología, Hospital de Osuna, Sevilla, Spain. inesvelas@msn.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Spontaneous
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surgery* Anti-Infective Agents, Local / adverse effects*, pharmacokinetics, urine Dilatation and Curettage* Female Humans Povidone-Iodine / adverse effects*, pharmacokinetics Pregnancy Pregnancy Complications / chemically induced* Pregnancy Trimester, First Prospective Studies Thyroid Diseases / chemically induced* Thyrotropin / metabolism Thyroxine / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Anti-Infective Agents, Local; 25655-41-8/Povidone-Iodine; 7488-70-2/Thyroxine; 9002-71-5/Thyrotropin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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