Document Detail


Use of postmenopausal hormones and risk of myocardial infarction.
MedLine Citation:
PMID:  7237723     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Information was collected by mail survey about myocardial infarction (MI), use of female hormones after menopause, and coronary risk factors 121,964 registered nurses ages 30-55 years. One hundred twenty-three women with a known type of prior menopause reported hospitalization for MI. Overall, use of female hormones by these women was very similar to that of control women matched for age and type of menopause. Compared with nonusers, the relative risk (RR) for women who had ever taken female hormones was 0.9 (95% confidence limits 0.6-1.2), and for current users the RR was 0.7 (0.5-1.1). For women with bilateral oophorectomy, the RR for current users was 0.4 (0.2-0.8). These data imply that, at present, a decision to prescribe postmenopausal hormones should be based primarily on weighing possible benefits from the relief of menopausal symptoms against unknown or suspected risks of other diseases, particularly uterine cancer in women with an intact uterus.
Authors:
C Bain; W Willett; C H Hennekens; B Rosner; C Belanger; F E Speizer
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Circulation     Volume:  64     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1981 Jul 
Date Detail:
Created Date:  1981-08-10     Completed Date:  1981-08-10     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  42-6     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Estrogens / adverse effects,  therapeutic use*
Female
Humans
Menopause*
Middle Aged
Myocardial Infarction / etiology*
Ovary / surgery
Risk
Smoking
Time Factors
Grant Support
ID/Acronym/Agency:
CA 16886/CA/NCI NIH HHS; CA 23645/CA/NCI NIH HHS; HL 24074/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Estrogens

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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