Document Detail


Use of positron emission tomography in initial staging of nonsmall cell lung carcinoma: a regional teaching hospital experience.
MedLine Citation:
PMID:  22524768     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The ability to accurately diagnose mediastinal lymph node involvement is significantly important in patients with nonsmall cell lung cancer (NSCLC). Positron emission tomography (PET) imaging has become a standard technique to assess lymph node involvement in patients with NSCLC. The purpose of this study is to evaluate the accuracy of PET scan imaging as a mediastinal staging tool in patients with NSCLC at our regional teaching institution. We performed a single-institution, retrospective review of patients diagnosed with NSCLC from January 1, 2006, through December 31, 2007. We included only those patients who underwent computed tomography (CT), PET, and pathologic assessment of mediastinal lymph nodes. Using pathologic assessment as the criterion standard, the overall accuracy, sensitivity, specificity, and positive and negative predictive values of CT and PET were calculated. One hundred seventeen patients were identified for inclusion in the study. The overall accuracy was 81.2 per cent for CT and 91.5 per cent for PET. Sensitivity was 42.1 per cent for CT and 52.6 per cent for PET. Specificity was 88.8 per cent for CT and 99.0 per cent for PET. Positive predictive values were 42.1 per cent for CT and 90.9 per cent for PET; negative predictive values were 88.8 per cent for CT and 91.5 per cent for PET. False-negative result rates were 9.4 per cent for CT and 7.7 per cent for PET; false-positive result rates were 9.4 per cent for CT and 0.9 per cent for PET. Our analysis confirms the use of PET scan imaging in the staging of patients with NSCLC at a regional teaching institution.
Authors:
Carl T Geraldson; James E Stephenson; James P Lagrew; Christine M Schammel; David P Schammel; Ryan A Greene; William D Bolton
Related Documents :
22422098 - Nuclear medicine imaging in tuberculosis using commercially available radiopharmaceutic...
24310468 - Rathke's cleft cyst with non-hemorrhagic rupture resulting in alteration of signal inte...
22389138 - Intraoperative mri electrical noise and monitor ecg filters affect arrhythmia detection...
22574268 - Neuroimaging features of xeroderma pigmentosum group a.
11479008 - Age related signal decrease in functional magnetic resonance imaging during motor stimu...
8606248 - Mr appearance of distal femoral cortical irregularity (cortical desmoid).
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American surgeon     Volume:  78     ISSN:  1555-9823     ISO Abbreviation:  Am Surg     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-04-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370522     Medline TA:  Am Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  305-8     Citation Subset:  IM    
Affiliation:
Furman University, Greenville, South Carolina, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Extrahepatic Portal Vein Ligation in Major Hepatectomies Performed under Selective Vascular Exclusio...
Next Document:  Clinical features and management of pseudoaneurysmal bleeding after pancreatoduodenectomy.