Document Detail


Use of platelet-rich plasma for the treatment of refractory jumper's knee.
MedLine Citation:
PMID:  19641918     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study was to evaluate the efficacy of multiple platelet-rich plasma (PRP) injections on the healing of chronic refractory patellar tendinopathy after previous classical treatments have failed. We treated 15 patients affected by chronic jumper's knee, who had failed previous nonsurgical or surgical treatments, with multiple PRP injections and physiotherapy. We also compared the clinical outcome with a homogeneous group of 16 patients primarily treated exclusively with the physiotherapy approach. Multiple PRP injections were performed on three occasions two weeks apart into the site of patellar tendinopathy. Tegner, EQ VAS and pain level were used for clinical evaluation before, at the end of the treatment and at six months follow-up. Complications, functional recovery and patient satisfaction were also recorded. A statistically significant improvement in all scores was observed at the end of the PRP injections in patients with chronic refractory patellar tendinopathy and a further improvement was noted at six months, after physiotherapy was added. Moreover, comparable results were obtained with respect to the less severe cases in the EQ VAS score and pain level evaluation, as in time to recover and patient satisfaction, with an even higher improvement in the sport activity level achieved in the PRP group. The clinical results are encouraging, indicating that PRP injections have the potential to promote the achievement of a satisfactory clinical outcome, even in difficult cases with chronic refractory tendinopathy after previous classical treatments have failed.
Authors:
Giuseppe Filardo; Elizaveta Kon; Stefano Della Villa; Ferruccio Vincentelli; Pier Maria Fornasari; Maurilio Marcacci
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Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2009-07-31
Journal Detail:
Title:  International orthopaedics     Volume:  34     ISSN:  1432-5195     ISO Abbreviation:  Int Orthop     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-19     Completed Date:  2010-11-15     Revised Date:  2013-06-02    
Medline Journal Info:
Nlm Unique ID:  7705431     Medline TA:  Int Orthop     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  909-15     Citation Subset:  IM    
Affiliation:
Department of Orthopedic and Sports Trauma, Rizzoli Orthopaedic Institute, Bologna, Italy. g.filardo@biomec.ior.it
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Athletic Injuries / therapy
Case-Control Studies
Humans
Injections, Intra-Articular
Knee Injuries / therapy
Knee Joint*
Male
Pain Measurement
Patient Satisfaction
Platelet-Rich Plasma*
Recovery of Function
Tendinopathy / therapy*
Wound Healing*
Young Adult
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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