Document Detail


Use of plasma receptor test for HCG in fertility regulation.
MedLine Citation:
PMID:  12336039     Owner:  PIP     Status:  MEDLINE    
Abstract/OtherAbstract:
A highly sensitive and specific pregnancy test, based on a radio-ligand assay system, is described; it was developed out of a need for more precision in pregnancy testing in a country which advocates menstrual regulation for pregnancy termination. The assay is based on identification of human chorionic gonadotropin by a plasma receptor and labeled antigen, and can be performed in about 60 minutes. Results of 428 serum samples collected from various clinical conditions were presented; these showed that the test had an accuracy of 99.7% in positive samples. Confirmation of these results was made by clinical follow-up, bioassays, histopathology, and radioimmunoassays. The only disadvantage to this test is the necessity for a radio-labeled isotope, and hence it can only be performed in areas and laboratories so equipped. The test's usefulness in cases of ectopic pregnancy, menstrual regulation, and threatened abortions is emphasized.
Authors:
S M Shahani; P P Kulkarni; K L Patel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of obstetrics and gynaecology of India     Volume:  29     ISSN:  0971-9202     ISO Abbreviation:  J Obstet Gynaecol India     Publication Date:  1979 Aug 
Date Detail:
Created Date:  1980-06-10     Completed Date:  1980-06-10     Revised Date:  2011-03-08    
Medline Journal Info:
Nlm Unique ID:  0374763     Medline TA:  J Obstet Gynaecol India     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  831-9     Citation Subset:  J    
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MeSH Terms
Descriptor/Qualifier:
Biology
Chorionic Gonadotropin*
Diagnosis
Endocrine System
Gonadotropins
Hormones
Laboratory Techniques and Procedures*
Membrane Proteins
Physiology
Pregnancy Tests
Pregnancy Tests, Immunologic*
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin; 0/Gonadotropins; 0/Hormones; 0/Membrane Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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