Document Detail

Use of plasma receptor test for HCG in fertility regulation.
MedLine Citation:
PMID:  12336039     Owner:  PIP     Status:  MEDLINE    
A highly sensitive and specific pregnancy test, based on a radio-ligand assay system, is described; it was developed out of a need for more precision in pregnancy testing in a country which advocates menstrual regulation for pregnancy termination. The assay is based on identification of human chorionic gonadotropin by a plasma receptor and labeled antigen, and can be performed in about 60 minutes. Results of 428 serum samples collected from various clinical conditions were presented; these showed that the test had an accuracy of 99.7% in positive samples. Confirmation of these results was made by clinical follow-up, bioassays, histopathology, and radioimmunoassays. The only disadvantage to this test is the necessity for a radio-labeled isotope, and hence it can only be performed in areas and laboratories so equipped. The test's usefulness in cases of ectopic pregnancy, menstrual regulation, and threatened abortions is emphasized.
S M Shahani; P P Kulkarni; K L Patel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of obstetrics and gynaecology of India     Volume:  29     ISSN:  0971-9202     ISO Abbreviation:  J Obstet Gynaecol India     Publication Date:  1979 Aug 
Date Detail:
Created Date:  1980-06-10     Completed Date:  1980-06-10     Revised Date:  2011-03-08    
Medline Journal Info:
Nlm Unique ID:  0374763     Medline TA:  J Obstet Gynaecol India     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  831-9     Citation Subset:  J    
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MeSH Terms
Chorionic Gonadotropin*
Endocrine System
Laboratory Techniques and Procedures*
Membrane Proteins
Pregnancy Tests
Pregnancy Tests, Immunologic*
Reg. No./Substance:
0/Chorionic Gonadotropin; 0/Gonadotropins; 0/Hormones; 0/Membrane Proteins

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