Document Detail


Use of pefloxacin in urogenital infections.
MedLine Citation:
PMID:  1462279     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Forty-three patients suffering from acute or chronic urinary tract infections have been treated with pefloxacin at the Department of Urology of St. Istán Hospital. Twenty-three patients received oral doses (2 x 400 mg), 1 tabl. in the mornings and 1 in the evenings. Eighteen patients were given 2 x 1 intravenous ampoule (2 x 400 mg) dissolved in 250 ml 5% glucose in slow drip infusion. Both the oral and intravenous doses were given in the patients for 10 days. In two patients complications was observed--in one case rhagades were formed on the lip and face due to photo-sensibilization, in the other case the drug administration had to be discontinued because of nausea and vomiting. These symptoms ceased after the discontinuance of the drug. The clinical conditions, the routes of administration, clinical and bacteriological results are summarized in tables. On the basis of a low number of cases it has been concluded that pefloxacin is a new valuable antibacterial drug the use of which resulted in recovery in 15 out of 18 patients' acute and chronic infections of the urogenital system.
Authors:
S Csata; T Bocskai
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Therapia Hungarica (English edition)     Volume:  40     ISSN:  0133-3909     ISO Abbreviation:  Ther Hung     Publication Date:  1992  
Date Detail:
Created Date:  1993-01-12     Completed Date:  1993-01-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8706535     Medline TA:  Ther Hung     Country:  HUNGARY    
Other Details:
Languages:  eng     Pagination:  72-5     Citation Subset:  IM    
Affiliation:
Department of Urology, Municipal St. István Hospital-Outpatient Clinic, Budapest.
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Adult
Aged
Female
Female Urogenital Diseases / diagnosis,  drug therapy*,  microbiology
Humans
Hungary
Infection / diagnosis,  drug therapy*,  microbiology
Infusions, Intravenous
Male
Male Urogenital Diseases*
Middle Aged
Outpatient Clinics, Hospital
Pefloxacin / administration & dosage,  therapeutic use*
Chemical
Reg. No./Substance:
70458-92-3/Pefloxacin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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