Document Detail


Use of peak expiratory flow for assessing bronchodilator responsiveness.
MedLine Citation:
PMID:  18923799     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Lung function in 1686 adult patients was measured before, and 15 minutes after, salbutamol inhalation. Bronchodilator responsiveness (BDR) was defined as a 12% improvement over baseline in either FEV1 or FVC, along with an absolute volume increment of 200 ml. Peak expiratory flow (PEF) change, both absolute and relative to baseline, was also calculated (DeltaPEF and DeltaPEF%, respectively). Change in PEF significantly correlated with change in FEV1. However, DeltaPEF and DeltaPEF% had poor discrimination in identifying BDR, with all specific cutoff values for DeltaPEF and DeltaPEF% having low or moderate sensitivity, specificity and predictive values.
Authors:
Ashutosh N Aggarwal; Ritesh Agarwal; Dheeraj Gupta; Surinder K Jindal
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Primary care respiratory journal : journal of the General Practice Airways Group     Volume:  18     ISSN:  1475-1534     ISO Abbreviation:  Prim Care Respir J     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-03-16     Completed Date:  2009-06-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101121543     Medline TA:  Prim Care Respir J     Country:  England    
Other Details:
Languages:  eng     Pagination:  50-2     Citation Subset:  IM    
Affiliation:
Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India. ashutosh@indiachest.org
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Bronchodilator Agents / therapeutic use*
Female
Forced Expiratory Volume
Humans
Male
Middle Aged
Peak Expiratory Flow Rate*
Predictive Value of Tests
Primary Health Care
Young Adult
Chemical
Reg. No./Substance:
0/Bronchodilator Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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