| Use of palivizumab and infection control measures to control an outbreak of respiratory syncytial virus in a neonatal intensive care unit confirmed by real-time polymerase chain reaction. | |
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MedLine Citation:
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PMID: 21330007 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Respiratory syncytial virus (RSV) is a potentially life-threatening infection in premature infants. We report an outbreak involving four infants in the neonatal intensive care unit (NICU) of our hospital that occurred in February 2010. RSV A infection was confirmed by real-time polymerase chain reaction. Palivizumab was administered to all infants in the NICU. There were no additional symptomatic cases and repeat RSV surveillance confirmed that there was no further cross-transmission within the unit. The outbreak highlighted the infection control challenge of very high bed occupancy in the unit and the usefulness of molecular methods in facilitating detection and management. |
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Authors:
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K O'Connell; T W Boo; D Keady; U Niriain; D O'Donovan; M Commane; C Faherty; M Cormican |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2011-02-16 |
Journal Detail:
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Title: The Journal of hospital infection Volume: 77 ISSN: 1532-2939 ISO Abbreviation: J. Hosp. Infect. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-03-22 Completed Date: 2011-07-18 Revised Date: 2012-09-13 |
Medline Journal Info:
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Nlm Unique ID: 8007166 Medline TA: J Hosp Infect Country: England |
Other Details:
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Languages: eng Pagination: 338-42 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 the Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Clinical Microbiology, University College Hospital, Galway, Ireland. karinaoconnell@gmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antibodies, Monoclonal
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administration & dosage* Antibodies, Monoclonal, Humanized Antiviral Agents / administration & dosage* Cross Infection / drug therapy, epidemiology*, prevention & control DNA, Viral / genetics, isolation & purification Disease Outbreaks* Female Genotype Humans Infant Infant, Newborn Infection Control / methods Intensive Care, Neonatal Polymerase Chain Reaction Respiratory Syncytial Virus Infections / drug therapy, epidemiology*, prevention & control Respiratory Syncytial Virus, Human / classification, drug effects, genetics, isolation & purification* |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Monoclonal; 0/Antibodies, Monoclonal, Humanized; 0/Antiviral Agents; 0/DNA, Viral; 0/palivizumab |
| Comments/Corrections | |
Comment In:
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J Hosp Infect. 2012 Aug;81(4):292-3
[PMID:
22727129
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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