Document Detail

Use of nitroglycerin in the treatment of acute heart failure and cardiogenic shock in patients with myocardial infarction.
MedLine Citation:
PMID:  3109805     Owner:  NLM     Status:  MEDLINE    
The effectiveness of nitroglycerin in the treatment of acute heart failure was investigated in 100 patients with myocardial infarction. It was found that nitroglycerin has marked advantages in comparison with cardiac glycosides both as regards its effectiveness and as regards the character of its action on the haemodynamics and the state of the periinfarction zone. In most patients (78%), a favourable effect was attained with intravenous nitroglycerin administration and with additional intake in the form of tablets. Clinical improvement was preceded by normalization of pulmonary artery pressure. Uninterrupted nitroglycerin administration was terminated after normalization and stabilization of haemodynamics. The results showed that with monitoring haemodynamics nitroglycerin can be administered also in haemodynamic disorders, which occur in the early period of cardiogenic shock.
N E Belskii; V A Pilipenko; S I Roshchin; A I Shira; I S Gilmar
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cor et vasa     Volume:  29     ISSN:  0010-8650     ISO Abbreviation:  Cor Vasa     Publication Date:  1987  
Date Detail:
Created Date:  1987-08-10     Completed Date:  1987-08-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372614     Medline TA:  Cor Vasa     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  89-97     Citation Subset:  IM    
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MeSH Terms
Acute Disease
Cardiac Glycosides / administration & dosage
Diuretics / administration & dosage
Drug Therapy, Combination
Heart Failure / drug therapy*
Hemodynamics / drug effects
Middle Aged
Myocardial Infarction / complications*
Nitroglycerin / adverse effects,  pharmacology,  therapeutic use*
Shock, Cardiogenic / drug therapy*
Reg. No./Substance:
0/Cardiac Glycosides; 0/Diuretics; 55-63-0/Nitroglycerin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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