Document Detail

Use of a new cardiac pacing mode designed to eliminate unnecessary ventricular pacing.
MedLine Citation:
PMID:  16627417     Owner:  NLM     Status:  MEDLINE    
AIMS: To examine the performance of AAIsafeR2, a new pacing mode to minimize the cumulative proportion of ventricular pacing in patients who do not need regular ventricular support. METHODS AND RESULTS: The safety of AAIsafeR2 was examined in 123 recipients (73 +/- 12 years old, 51% men) of dual chamber pacemakers implanted for sinus node dysfunction, paroxysmal AV block or the bradycardia-tachycardia syndrome. Data were collected from pacemaker diagnostics, and the first 43 patients underwent 24-h Holter recordings before being discharged from the hospital with AAIsafeR2 activated. No adverse event related to AAIsafeR2 was observed. All ventricular pauses detected on Holter tapes triggered immediate back-up ventricular pacing. Appropriate switches to DDD occurred in 97 of 123 patients. In 69 of 123 devices (56%) switches to DDD were non-sustained, and the average % ventricular pacing in this group was 0.2+/-0.5%. CONCLUSION: AAIsafeR2 mode seems to be safe and reliable in patients with infrequent slowing or pauses in ventricular activity, while maintaining ventricular pacing below 1%.
Gerd Fröhlig; Daniel Gras; Jacques Victor; Philippe Mabo; Daniel Galley; Arnaud Savouré; Gaël Jauvert; Pascal Defaye; Pascale Ducloux; Amel Amblard
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-01-09
Journal Detail:
Title:  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology     Volume:  8     ISSN:  1099-5129     ISO Abbreviation:  Europace     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-04-21     Completed Date:  2006-06-28     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  100883649     Medline TA:  Europace     Country:  England    
Other Details:
Languages:  eng     Pagination:  96-101     Citation Subset:  IM    
Medizinische Universitatsklinik III, Universitätskliniken des Saarlandes Innere Medizin III, Homburg Germany.
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MeSH Terms
Aged, 80 and over
Arrhythmias, Cardiac / therapy*
Cardiac Pacing, Artificial / adverse effects,  methods*
Electrocardiography, Ambulatory
Equipment Safety
Follow-Up Studies
Heart Atria / physiopathology
Heart Ventricles / physiopathology
Middle Aged
Pacemaker, Artificial*
Sinoatrial Node / physiopathology
Treatment Outcome

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