| Use of a mucolytic agent (Cytoclair) in the preparation of cell material for the detection of malignant cells in sputum. | |
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MedLine Citation:
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PMID: 670414 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A mucolytic agent, methyl cysteine HC1 (Cytoclair), has been used to obtain a centrifuged cell deposit for the detection of malignant cells in sputum. In 178 sputum samples from 52 patients with primary lung cancer there was a slightly higher rate of detection with the mucolytic method than with the routine method: 54 positives from 27 patients compared with 48 positives from 24 patients. Morphological studies using the mucolytic agent indicated that a millipore filter with fixation of cells in suspension produces a satisfactory cell preparation and is valuable in certain problem cases. |
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Authors:
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J M Grainger; O A Husain |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of clinical pathology Volume: 31 ISSN: 0021-9746 ISO Abbreviation: J. Clin. Pathol. Publication Date: 1978 Jun |
Date Detail:
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Created Date: 1978-09-30 Completed Date: 1978-09-30 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0376601 Medline TA: J Clin Pathol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 585-90 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cysteine
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analogs & derivatives*,
diagnostic use Expectorants / diagnostic use* Humans Lung Neoplasms / diagnosis*, pathology Methods Sputum / cytology* |
| Chemical | |
Reg. No./Substance:
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0/Expectorants; 52-90-4/Cysteine |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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