Document Detail

Use of misoprostol in first and second trimester abortion: a review.
MedLine Citation:
PMID:  10481856     Owner:  NLM     Status:  MEDLINE    
The use of misoprostol in medical termination of first and second term pregnancies and cervical priming in surgically induced termination of pregnancies has been studied extensively. A survey is given on the available literature (MEDLINE to May 1998) on the usage as a single medication or in combination with mifepristone or methotrexate. A review is given on literature concerning side effects and complications. Misoprostol is a most promising, cheap, and effective agent, which does not need cool storage like other prostaglandins. The use of misoprostol as an abortifacient has, however, not been supported by the manufacturer. This leads to the situation (similar to mifepristone/RU 486) that it is used and researched, but probably will not be officially approved for this specific indication.
H C Scheepers; E J van Erp; A S van den Bergh
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Obstetrical & gynecological survey     Volume:  54     ISSN:  0029-7828     ISO Abbreviation:  Obstet Gynecol Surv     Publication Date:  1999 Sep 
Date Detail:
Created Date:  1999-10-21     Completed Date:  1999-10-21     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0401007     Medline TA:  Obstet Gynecol Surv     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  592-600     Citation Subset:  IM    
Department of Gynaecology and Obstetrics, Leyenburg Hospital, The Hague, The Netherlands.
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MeSH Terms
Abortifacient Agents, Nonsteroidal* / adverse effects
Abortifacient Agents, Steroidal
Misoprostol* / adverse effects
Pregnancy Trimester, First
Pregnancy Trimester, Second
Reg. No./Substance:
0/Abortifacient Agents, Nonsteroidal; 0/Abortifacient Agents, Steroidal; 59122-46-2/Misoprostol; 84371-65-3/Mifepristone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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