| Use of methotrexate in patients with sarcoidosis. | |
| | |
MedLine Citation:
|
PMID: 21044457 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Sarcoidosis may present with symptoms related to involvement of joints, skin and lungs, as well as other organs. Corticosteroids are the basis of treatment of symptomatic sarcoidosis. Additional or alternative drugs may be required in chronic cases and when systemic corticosteroids are contraindicated. Cytotoxic agents seem to be of value in selected patients, but no controlled studies are available, and the published literature consists of small case series. Therefore, no international agreement exists regarding when these drugs should be used in patients with sarcoidosis. Methotrexate is generally the preferred agent for treatment of chronic sarcoidosis when corticosteroids have inadequate efficacy and/or severe adverse effects. In this review we discuss the available literature concerning the treatment of sarcoidosis with methotrexate. |
| | |
Authors:
|
U Kiltz; J Braun |
Related Documents
:
|
17492847 - Ace inhibitor in the treatment of cutaneous and lymphatic sarcoidosis. 8235667 - Pulmonary alveolar hemorrhage in systemic lupus erythematosus. 21869907 - Upper urinary tract urothelial carcinoma: what have we learned in the last 4 years? 20429007 - Juvenile systemic lupus erythematosus and dermatomyositis associated with urticarial va... 12452497 - Dracunculiasis eradication: and now, sudan. 17827847 - Two cases of acute exacerbation of interstitial pneumonia treated with polymyxin b-immo... |
Publication Detail:
|
Type: Journal Article; Review Date: 2010-10-28 |
Journal Detail:
|
Title: Clinical and experimental rheumatology Volume: 28 ISSN: 0392-856X ISO Abbreviation: Clin. Exp. Rheumatol. Publication Date: 2010 Sep-Oct |
Date Detail:
|
Created Date: 2010-11-03 Completed Date: 2010-12-21 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8308521 Medline TA: Clin Exp Rheumatol Country: Italy |
Other Details:
|
Languages: eng Pagination: S183-5 Citation Subset: IM |
Affiliation:
|
Rheumazentrum Ruhrgebiet, Herne, Germany. kiltz@rheumazentrum-ruhrgebiet.de |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adrenal Cortex Hormones
/
therapeutic use Anti-Inflammatory Agents / therapeutic use* Chronic Disease Evidence-Based Medicine Humans Methotrexate / therapeutic use* Sarcoidosis / drug therapy* Sarcoidosis, Pulmonary / drug therapy Treatment Outcome |
| Chemical | |
Reg. No./Substance:
|
0/Adrenal Cortex Hormones; 0/Anti-Inflammatory Agents; 59-05-2/Methotrexate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Use of methotrexate in ANCA-associated vasculitides.
Next Document: Inhibitory effect of antisense VEGF₁₂₁ and endostatin genes transfection on tumor growth and m...