Document Detail


Use of medroxyprogesterone acetate in the treatment of Müllerian adenosarcoma: a case report.
MedLine Citation:
PMID:  11925144     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Müllerianadenosarcoma is a rare pelvic malignancy that most commonly arises from the endometrium. These tumors are relatively insensitive to chemotherapy and radiation and are primarily treated by surgical resection. We report a case of müllerian adenosarcoma arising outside of the uterus from a background of endometriosis treated with a combination of surgical resection and medroxyprogesterone acetate. CASE: A 43-year-old woman with a history of endometriosis was diagnosed with advanced extrauterine müllerian adenosarcoma. After suboptimal tumor dubulking surgery she was treated with medroxyprogesterone acetate. Ten months postoperatively she remains without evidence of disease. CONCLUSION: Medroxyprogesterone acetate may be a useful drug in the treatment of advanced müllerian adenosarcoma.
Authors:
Brian J Hines; Robert F Porges; Kush Mittal; Franco M Muggia; John P Curtin
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Gynecologic oncology     Volume:  85     ISSN:  0090-8258     ISO Abbreviation:  Gynecol. Oncol.     Publication Date:  2002 Apr 
Date Detail:
Created Date:  2002-04-01     Completed Date:  2002-05-09     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0365304     Medline TA:  Gynecol Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  192-5     Citation Subset:  IM    
Affiliation:
Division of Gynecologic Oncology, New York University School of Medicine, New York, New York 10016, USA. hinesb@alum.mit.edu
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MeSH Terms
Descriptor/Qualifier:
Adenosarcoma / drug therapy*,  surgery
Adult
Antineoplastic Agents, Hormonal / therapeutic use*
Combined Modality Therapy
Endometriosis / complications
Female
Genital Neoplasms, Female / drug therapy*,  surgery
Humans
Medroxyprogesterone Acetate / therapeutic use*
Mixed Tumor, Mullerian / drug therapy*,  surgery
Chemical
Reg. No./Substance:
0/Antineoplastic Agents, Hormonal; 71-58-9/Medroxyprogesterone Acetate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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