Document Detail

[Use of intravitreal bevacizumab for the treatment of choroidal neovascularization secondary to choroidal rupture].
MedLine Citation:
PMID:  22040647     Owner:  NLM     Status:  MEDLINE    
CASE REPORT: A 28 year-old male attended our Emergency Department with a traumatic choroidal rupture and macular haemorrhage. After pneumatic displacement of the haemorrhage with C(3)F(8) and tissue plasminogen activator, the haemorrhage was reabsorbed and visual acuity (VA) improved. Three months later the patient presented with decreased VA and a juxtafoveal choroidal neovascularisation (CNV) that was treated with intravitreal bevacizumab. One year after a single bevacizumab injection the CNV remained inactive, with a final VA of 0.5.
DISCUSSION: Intravitreal bevacizumab injection is a new and effective treatment for traumatic CNV. In our patient, in contrast to other aetiologies, the CNV needed no more than one Avastin(®) injection to be inactivated, after one year of follow-up.
X Valldeperas; R Bonilla; M R Romano; J de la Cámara
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Publication Detail:
Type:  Case Reports; English Abstract; Journal Article     Date:  2011-09-13
Journal Detail:
Title:  Archivos de la Sociedad Española de Oftalmología     Volume:  86     ISSN:  1989-7286     ISO Abbreviation:  Arch Soc Esp Oftalmol     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-01     Completed Date:  2012-03-05     Revised Date:  2013-05-27    
Medline Journal Info:
Nlm Unique ID:  1304603     Medline TA:  Arch Soc Esp Oftalmol     Country:  Spain    
Other Details:
Languages:  spa     Pagination:  380-3     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Sociedad Española de Oftalmología. Published by Elsevier Espana. All rights reserved.
Servicio de Oftalmología, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, España.
Vernacular Title:
Bevacizumab intravítreo en el tratamiento de la neovascularización subretiniana secundaria a rotura coroidea.
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MeSH Terms
Antibodies, Monoclonal, Humanized / administration & dosage,  therapeutic use*
Bruch Membrane / injuries
Choroid / injuries*
Choroid Hemorrhage / etiology
Choroidal Neovascularization / drug therapy*,  etiology
Fluorescein Angiography
Fluorocarbons / administration & dosage,  therapeutic use
Intravitreal Injections
Rupture / complications
Tissue Plasminogen Activator / administration & dosage,  therapeutic use
Wounds, Nonpenetrating / complications
Reg. No./Substance:
0/Antibodies, Monoclonal, Humanized; 0/Fluorocarbons; 2S9ZZM9Q9V/bevacizumab; 76-19-7/perflutren; EC Plasminogen Activator

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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