Document Detail

Use of intrathecal and epidural morphine for pain relief in patients with malignant diseases: a preliminary report.
MedLine Citation:
PMID:  6960119     Owner:  NLM     Status:  MEDLINE    
The results of a preliminary study involving the treatment of various malignant pain disorders by intrathecal (I.T.) or epidural (E) morphine sulfate (M.S.) injections in 18 patients are reported. Fourteen (78%) patients obtained satisfactory analgesic effects and 4 (22%) failed. The overall duration of pain relief was modest and ranged from 10 to 72 hours; the intrathecal route provided a slightly longer duration (median: 48 hours; range: 15-72 hours) of analgesia than that of the epidural route (median: 20 hours; range: 10-72 hours). Minor and transient complications occurred in 10 (55%) patients.
R C Rico; G H Hobika; A M Avellanosa; R J Trudnowski; J Rempel; C R West
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of medicine     Volume:  13     ISSN:  0025-7850     ISO Abbreviation:  J Med     Publication Date:  1982  
Date Detail:
Created Date:  1983-02-25     Completed Date:  1983-02-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7505566     Medline TA:  J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  223-31     Citation Subset:  IM    
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MeSH Terms
Adenocarcinoma / complications,  drug therapy*
Epidural Space
Headache / chemically induced
Injections, Spinal
Middle Aged
Morphine / administration & dosage,  adverse effects,  therapeutic use*
Nausea / chemically induced
Pain / drug therapy*,  etiology
Time Factors
Vomiting / chemically induced
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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