Document Detail

Use of interstitial hyperthermia to produce homogeneous heat distribution patterns.
MedLine Citation:
PMID:  3560247     Owner:  NLM     Status:  MEDLINE    
The preliminary experience of the use of a prototype hyperthermia unit (Astro 200) for tumor regression in Howard University Hospital's Department of Radiotherapy is described. The purpose of this study was to produce homogeneous heat distribution patterns within a 5-cm cylinder in the middle of a phantom (ground beef) using radio frequency conducted through electrodes implanted in the medium. Homogeneous heat distribution was achieved by finding the optimal spatial distribution of electrodes within the phantom and by sequencing the radio frequency in the electrodes. Monitored observation revealed a steady state homogeneous temperature of 42.5 °C within a 4-cm diameter. There was a temperature difference of 0.5 °C within 1 cm of the periphery.Heat in the clinical range of 42 to 43 °C has caused tumor regression, and was found to be most effective when combined with another modality of radiation. At Howard University Hospital, hyperthermia is used in conjunction with conventional modalities-surgery, radiotherapy, and chemotherapy-in the treatment of tumors.
G C King; A L Goldson; F Galal; E Ashayeri
Related Documents :
7410757 - Effect of microwave heating in cook/chill foodservice systems. some data on temperature...
20568197 - A correlation for heat transfer coefficients in food extruders.
25263347 - Lc-esi-ms/ms analysis of phosphodiesterase-5 inhibitors and their analogues in foods an...
21871577 - Digesta retention time in the galápagos tortoise (chelonoidi nigra).
1822937 - Current status of food-borne parasitic zoonoses in korea.
11336487 - Comparison of permeating and nonpermeating cryoprotectants for mouse sperm cryopreserva...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the National Medical Association     Volume:  79     ISSN:  0027-9684     ISO Abbreviation:  J Natl Med Assoc     Publication Date:  1987 Feb 
Date Detail:
Created Date:  1987-04-27     Completed Date:  1987-04-27     Revised Date:  2010-10-26    
Medline Journal Info:
Nlm Unique ID:  7503090     Medline TA:  J Natl Med Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  189-92     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Body Temperature
Hyperthermia, Induced / instrumentation*
Neoplasms / therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Diagnosis of hyperthyroidism in patients with thyroiditis: a case study.
Next Document:  Metastasis to the umbilicus: possible racial difference.