Document Detail

Use of intense pulsed light and a retinyl-based cream as a potential treatment for cellulite: a pilot study.
MedLine Citation:
PMID:  17177749     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: There are few therapeutic treatments established for cellulite. OBJECTIVE: We studied the response of intense pulsed light (IPL) treatment with or without a compounded prescription retinyl-based cream on a small group of patients who had visible cellulite present on the buttocks and thigh regions. PATIENTS AND METHODS: Twenty patients were selected to complete a 12-week course of IPL treatment either with or without a retinyl-based cream. Assessment was based on visual evaluation, photographs, skin ultrasounds, and patient satisfaction. RESULTS: Fifteen (75%) completed the study, and nine (60%) had a self-improvement rating of >or= 50%. Seven (78%) of nine patients used IPL/cream. Of the remaining six (40%) completing the study, four (27%) had self-improvement ratings of 25-50% and two (13%; IPL only) were considered treatment failures with a rating of 10-25%. Both IPL/cream and IPL-only groups exhibited an improvement in the smoothness of the affected area even following weight gain. Skin ultrasounds confirmed an increase in the deposition of collagen. During an 8-month phone follow-up, 8 (67%) of 12 responding reported the same or improved results. CONCLUSION: IPL treatment with or without a retinyl-based cream can improve the appearance of peau d'orange cellulite, though the cream may augment cosmetic improvement. This approach is well tolerated, has minimal side effects, and is accompanied by a high degree of patient satisfaction.
Joshua S Fink; Harold Mermelstein; Andrew Thomas; Robert Trow
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of cosmetic dermatology     Volume:  5     ISSN:  1473-2165     ISO Abbreviation:  J Cosmet Dermatol     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-12-20     Completed Date:  2008-05-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101130964     Medline TA:  J Cosmet Dermatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  254-62     Citation Subset:  IM    
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MeSH Terms
Adipose Tissue*
Antioxidants / therapeutic use*
Follow-Up Studies
Laser Therapy*
Middle Aged
Obesity / pathology,  therapy*
Patient Satisfaction
Pilot Projects
Treatment Outcome
Vitamin A / analogs & derivatives*,  therapeutic use
Reg. No./Substance:
0/Antioxidants; 11103-57-4/Vitamin A; 79-81-2/retinol palmitate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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