| Use of an immunoradiometric assay and a radioimmunoassay for the detection of free beta-human chorionic gonadotropin. | |
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MedLine Citation:
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PMID: 2580254 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An immunoradiometric assay and a radioimmunoassay (RIA) were used to quantitate human chorionic gonadotropin (hCG) in the sera of ten pregnant women at term and of six women with gestational trophoblastic neoplasia. The two techniques show good correlation (Pearson correlation coefficient .96) in the assay of pregnancy serum. Because only the RIA, and not the immunoradiometric assay, measures the free beta-subunit of hCG, a comparison of the results obtained by the two immunoassay methods permits a semi-quantitative assessment of the free beta-subunit. The numerical results may not reflect the actual concentration of free beta-subunit in that two different immunoassay methods are used. |
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Authors:
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A I Shapiro; T F Wu; S C Ballon; E J Lamb |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 65 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 1985 Apr |
Date Detail:
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Created Date: 1985-05-01 Completed Date: 1985-05-01 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 545-9 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antibodies, Monoclonal Chorionic Gonadotropin / blood*, standards Chorionic Gonadotropin, beta Subunit, Human Female Humans Peptide Fragments / blood*, standards Pregnancy Radioimmunoassay / methods*, standards Reference Standards Trophoblastic Neoplasms / blood Uterine Neoplasms / blood |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Monoclonal; 0/Chorionic Gonadotropin; 0/Chorionic Gonadotropin, beta Subunit, Human; 0/Peptide Fragments |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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