| Use of fondaparinux in a pregnant woman with pulmonary embolism and heparin-induced thrombocytopenia. | |
| | |
MedLine Citation:
|
PMID: 21525816 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Background: A serious complication of heparin treatment, heparin-induced thrombocytopenia (HIT) is rarely observed in pregnant women. Drug therapy during pregnancy should always be chosen to minimize fetal risk. The management of HIT in pregnancy represents a medical challenge. Unlike heparins, the anticoagulants used in patients with HIT do cross the placenta, with unknown fetal effects.<br /> Case Report: We present a case of a 24-year-old female presenting for care at 34 weeks of gestation with acute pulmonary embolism treated initially with unfractionated heparin (UFH) and low molecular weight heparin (LMWH), who developed HIT. She was then successfully treated with fondaparinux.<br /> Conclusions: To the best of our knowledge, this is one of the first case reports describing a successful use of fondaparinux in the treatment of HIT in a third-trimester pregnant woman, providing a novel approach for this subset of patients.<br /> |
| | |
Authors:
|
Michał Ciurzyński; Krzysztof Jankowski; Bronisława Pietrzak; Natalia Mazanowska; Ewa Rzewuska; Robert Kowalik; Piotr Pruszczyk |
Related Documents
:
|
21207386 - Incremental cost of non-invasive prenatal diagnosis versus invasive prenatal diagnosis ... 7174966 - Milk progesterone for pregnancy diagnosis in dairy goats. 21293726 - Reproductive counselling. 21418386 - Consequences of fetal programming for cardiovascular disease in adulthood. 7156326 - Idiopathic acute fatty liver of pregnancy in 12 patients. 2350196 - Maternal and fetal prolactin in pregnancy-induced hypertension. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Medical science monitor : international medical journal of experimental and clinical research Volume: 17 ISSN: 1643-3750 ISO Abbreviation: Med. Sci. Monit. Publication Date: 2011 May |
Date Detail:
|
Created Date: 2011-04-28 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9609063 Medline TA: Med Sci Monit Country: Poland |
Other Details:
|
Languages: eng Pagination: CS56-59 Citation Subset: IM |
Affiliation:
|
Department of Internal Medicine and Cardiology, Medical University of Warsaw, Warsaw, Poland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Successful operative management of an intact second trimester abdominal pregnancy with additional pr...
Next Document: Needle aspiration with surgical excision of an epithelial posttraumatic iris cyst - a case report.