Document Detail


Use of fibrin sealant for reproductive surgery: a randomized study in the rabbit model.
MedLine Citation:
PMID:  8698266     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The present study was undertaken to compare adhesion formation and reproductive outcome after reproductive surgery with or without the application of fibrin sealant. At laparotomy, the ovaries and uterine horns of 20 rabbits were longitudinally incised on the antimesenteric side using a monopolar microneedle. At random, one ovary and the ipsilateral uterine horn were covered with fibrin sealant, while those on the contralateral side were left uncovered without application of sutures. The rabbits were then mated, and 2 weeks later a second-look laparotomy was performed by a blinded observer. No statistically significant differences were found in postoperative adhesions, number of corpora lutea in each ovary, number of embryos in the ipsilateral uterine horn, and nidation index for each side. Fibrin sealant for conservative surgery does not appear to significantly affect either postoperative adhesion formation or reproductive outcome.
Authors:
R Marana; L Muzii; G F Catalano; P Caruana; S Mancuso
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Gynecologic and obstetric investigation     Volume:  41     ISSN:  0378-7346     ISO Abbreviation:  Gynecol. Obstet. Invest.     Publication Date:  1996  
Date Detail:
Created Date:  1996-09-05     Completed Date:  1996-09-05     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7900587     Medline TA:  Gynecol Obstet Invest     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  199-202     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy.
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MeSH Terms
Descriptor/Qualifier:
Animals
Female
Fibrin Tissue Adhesive / therapeutic use*
Male
Ovarian Diseases / prevention & control*
Ovary / surgery*
Prospective Studies
Rabbits
Random Allocation
Tissue Adhesions / prevention & control
Tissue Adhesives / therapeutic use*
Uterine Diseases / prevention & control*
Uterus / surgery*
Chemical
Reg. No./Substance:
0/Fibrin Tissue Adhesive; 0/Tissue Adhesives

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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