| Use of diet, nutritional supplements and exercise in HIV-infected patients receiving combination antiretroviral therapies: a systematic review. | |
| | |
MedLine Citation:
|
PMID: 18505167 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The use of combination antiretroviral therapy (cART) has improved the prognosis of HIV infection, but it has also been linked to a spectrum of body composition changes and metabolic alterations known as the lipodystrophy syndrome. Nutritional status could influence body composition changes. METHODS: We performed a systematic search of published peer-reviewed data on the effects of diet, nutrition support and exercise on body composition and metabolic complications in patients receiving cART. RESULTS: Few controlled studies, most of them with small sample size, were found. Oral nutritional support increases protein and energy intake, and results in body weight and fat mass gains. Resistance exercise, with or without an aerobic component, increases lean mass and can improve insulin resistance. Low-fat diets or exercise can result in loss of fat mass, and they should be used with caution in subjects with lipoatrophy. CONCLUSIONS: Nutritional support and exercise result in small but significant body composition changes and can be used as complementary interventions. There is a need for further research on nutritional interventions in HIV-infected patients receiving cART. |
| | |
Authors:
|
Pere Leyes; Esteban Martínez; Maria de Talló Forga |
Related Documents
:
|
3967777 - Metabolism of substrates: energy substrate metabolism during exercise and as modified b... 21217817 - Establishing zebrafish as a novel exercise model: swimming economy, swimming-enhanced g... 21225277 - Physiological fitness and health adaptations from purposeful training using off-road ve... 20416577 - Physical activity-induced alterations on tissue lipid composition and lipid metabolism ... 7979927 - Elderly rheumatoid arthritis patients on steroid treatment tolerate physical training w... 10946767 - Quantitative image analysis of hyaluronan expression in human tooth germs. |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Antiviral therapy Volume: 13 ISSN: 1359-6535 ISO Abbreviation: Antivir. Ther. (Lond.) Publication Date: 2008 |
Date Detail:
|
Created Date: 2008-05-28 Completed Date: 2008-06-30 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9815705 Medline TA: Antivir Ther Country: England |
Other Details:
|
Languages: eng Pagination: 149-59 Citation Subset: IM |
Affiliation:
|
Nutrition and Dietetics Unit, Endocrinology Service, Hospital Clinic de Barcelona, 08036 Barcelona, Spain. pleyes@clinic.ub.es |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Anti-HIV Agents
/
adverse effects,
therapeutic use* Body Composition Diet* Dietary Supplements* Double-Blind Method Drug Therapy, Combination Exercise* HIV Infections / drug therapy* HIV-Associated Lipodystrophy Syndrome / prevention & control* Humans Nutritional Status Randomized Controlled Trials as Topic Reverse Transcriptase Inhibitors / adverse effects, therapeutic use* |
| Chemical | |
Reg. No./Substance:
|
0/Anti-HIV Agents; 0/Reverse Transcriptase Inhibitors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Arterial blood gas analysis. 2: compensatory mechanisms.
Next Document: A systematic review of T-cell epitopes in hepatitis B virus: identification, genotypic variation and...