Document Detail


Use of dicarboxylic acids and polyphenols to attenuate reticular pH drop and acute phase response in dairy heifers fed a high grain diet.
MedLine Citation:
PMID:  25425091     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BackgroundThe aim of this study was to determine the ability of two feed additives, a fumarate-malate (FM) and a polyphenol-essential oil mixture (PM), in attenuating the drop of ruminal pH and the metabolic and immune response resulting from an excessively high grain diet. Six heifers were used in a 3¿×¿3 Latin square experiment and fed a low starch (LS) diet for 14 d, followed by a high starch (HS) diet for 8 d (NDF 33.6%, starch 30.0% DM). In the last 5 days of each period, barley meal was added to decrease rumen pH. During HS feeding all animals were randomly assigned to one of the following three dietary treatments: no supplement/control (CT), a daily dose of 60 g/d of FM, or 100 g/d of PM. Reticular pH was continuously recorded using wireless boluses. On d 21 of each period, rumen fluid was collected by rumenocentesis (1400 h), together with blood (0800 h) and fecal samples (0800, 1400, and 2100 h).ResultsThe correlation coefficient of pH values obtained using the boluses and rumenocentesis was 0.83. Compared with CT and PM, the FM treatment led to a lower DMI. Nadir pH was lowest during CT (5.40, 5.69, and 5.62 for CT, FM and PM, respectively), confirming the effectiveness of both supplements in reducing the pH drop caused by high grain feeding. This result was confirmed by the highest average time spent daily below 5.6 pH (199, 16 and 18 min/d) and by the highest acetate to propionate ratio of the CT fed heifers. The PM decreased the concentrations of neutrophils (2.9, 3.2, and 2.8 109/L) and acute phase proteins: SAA (37.1, 28.6 and 20.1 ¿g/mL), LBP (4.1, 3.8, and 2.9 ¿g/mL), and Hp (675, 695 and 601 ¿g/mL). Free lipopolysaccharides (LPS) were detected in blood and feces, but their concentrations were not affected by treatments, as the remaining blood variables.ConclusionsData suggest that both additives could be useful in attenuating the effects of excessive grain feeding on rumen pH, but the PM supplement was more effective than FM in reducing the inflammatory response compared to CT.
Authors:
Roberta De Nardi; Giorgio Marchesini; Kees Plaizier; Shucong Li; Ehsan Khafipour; Rebecca Ricci; Igino Andrighetto; Severino Segato
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-11-26
Journal Detail:
Title:  BMC veterinary research     Volume:  10     ISSN:  1746-6148     ISO Abbreviation:  BMC Vet. Res.     Publication Date:  2014 Nov 
Date Detail:
Created Date:  2014-11-26     Completed Date:  -     Revised Date:  2014-11-27    
Medline Journal Info:
Nlm Unique ID:  101249759     Medline TA:  BMC Vet Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  277     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Efficient hybrid white organic light-emitting diodes with extremely long lifetime: the effect of n-t...
Next Document:  Salicylate-containing rubefacients for acute and chronic musculoskeletal pain in adults.