| Use of corticosteroids in combination with antimicrobial drugs in the treatment of infectious corneal disease. | |
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MedLine Citation:
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PMID: 1866135 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The use of corticosteroids in the management of infectious eye disease is controversial. In this study, the authors attempt to analyze the goals and risks of the use of corticosteroids in the treatment of various forms of infectious keratitis with reference to generally recognized principles for the treatment of infectious diseases. Existing clinical and research data are reviewed in this context to make appropriate recommendations for the use of corticosteroids in the treatment of bacterial, fungal, and acanthamoeba keratitis. The authors conclude that corticosteroids are definitely contraindicated in the treatment of fungal keratitis, and relatively contraindicated in the treatment of Acanthamoeba keratitis. Topical corticosteroid therapy may have a role in the treatment of bacterial keratitis if appropriate guidelines are followed. |
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Authors:
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G A Stern; M Buttross |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Ophthalmology Volume: 98 ISSN: 0161-6420 ISO Abbreviation: Ophthalmology Publication Date: 1991 Jun |
Date Detail:
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Created Date: 1991-09-12 Completed Date: 1991-09-12 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7802443 Medline TA: Ophthalmology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 847-53 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, University of Florida College of Medicine, Gainesville 32610. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acanthamoeba Keratitis
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drug therapy Adrenal Cortex Hormones / administration & dosage, contraindications, therapeutic use* Anti-Bacterial Agents / administration & dosage, therapeutic use* Drug Therapy, Combination Eye Infections / drug therapy* Eye Infections, Bacterial / drug therapy Eye Infections, Fungal / drug therapy Humans Keratitis / drug therapy*, microbiology |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones; 0/Anti-Bacterial Agents |
| Comments/Corrections | |
Comment In:
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Ophthalmology. 1991 Jun;98(6):845-6
[PMID:
1866134
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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