Document Detail


Use of color and power Doppler sonography to identify feeding arteries associated with parathyroid adenomas.
MedLine Citation:
PMID:  9725323     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The objective of our study was to determine the value of using color and power Doppler sonography to reveal extrathyroidal feeding arteries in the detection of abnormal parathyroid glands. SUBJECTS AND METHODS: Forty-four patients with primary hyperparathyroidism were imaged prospectively with high-resolution gray-scale, color flow, and power Doppler sonography. The presence of extrathyroidal arteries supplying the adenomas was noted. All patients underwent subsequent neck exploration. The locations of the abnormal glands were recorded. RESULTS: At surgery, 51 abnormal parathyroid glands were removed in the 44 patients. Sonography correctly revealed an adenoma in 40 of the 44 patients. Likewise, sonography revealed 42 of the 51 adenomas. Nine false-negative and two false-positive interpretations of the sonograms were made. Thus, overall sensitivity was 83%, specificity was 98%, and accuracy was 94%. Three of the false-negative interpretations were ectopic glands within the superior mediastinum. Excluding these three glands from analysis, the sensitivity for detection of adenomas within the neck was 88%, specificity was 98%, and accuracy was 95%. An extrathyroidal artery leading to a parathyroid adenoma was seen in 35 of the 42 adenomas revealed by sonography. The presence of an extrathyroidal artery leading to an adenoma was found to aid in the detection of an otherwise inconspicuous parathyroid gland in five patients, which improved sensitivity from 73% to 83%. CONCLUSION: Prominent vessels supplying parathyroid adenomas are frequently revealed by color flow and power Doppler sonography. These vessels can serve as "road maps" to abnormal parathyroid glands.
Authors:
M J Lane; T S Desser; R J Weigel; R B Jeffrey
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  171     ISSN:  0361-803X     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  1998 Sep 
Date Detail:
Created Date:  1998-09-16     Completed Date:  1998-09-16     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  819-23     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiology, Stanford University Hospital and School of Medicine, CA 94305, USA.
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MeSH Terms
Descriptor/Qualifier:
Adenoma / blood supply*,  ultrasonography*
Adult
Aged
Female
Humans
Hyperparathyroidism / ultrasonography
Male
Middle Aged
Parathyroid Neoplasms / blood supply*,  ultrasonography*
Predictive Value of Tests
Prospective Studies
Sensitivity and Specificity
Ultrasonography, Doppler, Color*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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