Document Detail


Use of cisplatin for control of metastatic malignant mesenchymoma and hypertrophic osteopathy in a dog.
MedLine Citation:
PMID:  2768061     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cisplatin (cis-diammine-dichloroplatinum) treatment induced partial remission of pulmonary metastatic malignant mesenchymoma and nearly complete radiographic remission of hypertrophic osteopathy in a 14-year-old Beagle. Cisplatin was given once every 3 weeks. Clinical signs of hypertrophic osteopathy resolved one week after initiation of treatment. Partial remission of pulmonary metastases and partial radiographic remission of hypertrophic osteopathy was seen 6 weeks after initiation of treatment. Previous treatment of neoplasia-related hypertrophic osteopathy has consisted of removal of the initiating mass or vagotomy. In this case, appropriate chemotherapy was used to control clinical signs and progression of hypertrophic osteopathy.
Authors:
K A Hahn; R C Richardson
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of the American Veterinary Medical Association     Volume:  195     ISSN:  0003-1488     ISO Abbreviation:  J. Am. Vet. Med. Assoc.     Publication Date:  1989 Aug 
Date Detail:
Created Date:  1989-10-06     Completed Date:  1989-10-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7503067     Medline TA:  J Am Vet Med Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  351-3     Citation Subset:  IM    
Affiliation:
Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907-7403.
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MeSH Terms
Descriptor/Qualifier:
Animals
Bone Diseases / complications,  drug therapy,  veterinary*
Cisplatin / therapeutic use*
Dog Diseases / drug therapy*
Dogs
Female
Hypertrophy
Lung Neoplasms / drug therapy,  secondary,  veterinary*
Mesenchymoma / complications,  drug therapy,  secondary,  veterinary*
Skin Neoplasms / complications,  drug therapy,  veterinary
Soft Tissue Neoplasms / complications,  drug therapy,  veterinary
Chemical
Reg. No./Substance:
15663-27-1/Cisplatin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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