Document Detail


Use of cardiac biomarkers in end-stage renal disease.
MedLine Citation:
PMID:  18322158     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Mortality among patients with ESRD remains high because of an excessive cardiovascular risk related to a very high incidence of cardiac hypertrophy, cardiomyopathy, heart failure, and coronary artery disease. Identifying serum biomarkers that are useful in profiling cardiovascular risk and enabling stratification of early mortality and cardiovascular risk is an important goal in the treatment of these patients. This review examines current evidence pertaining to the role and utility of two emerging cardiac biomarkers, B-type natriuretic peptide and cardiac troponin T, in patients with ESRD. Together, these data demonstrate how these two cardiac biomarkers may play an adjunctive role to echocardiography in assessing cardiovascular risk and how they may aid in the clinical treatment of these patients.
Authors:
Angela Yee-Moon Wang; Kar-Neng Lai
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2008-03-05
Journal Detail:
Title:  Journal of the American Society of Nephrology : JASN     Volume:  19     ISSN:  1533-3450     ISO Abbreviation:  J. Am. Soc. Nephrol.     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-08-27     Completed Date:  2008-10-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9013836     Medline TA:  J Am Soc Nephrol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1643-52     Citation Subset:  IM    
Affiliation:
University Department of Medicine, Queen Mary Hospital, University of Hong Kong, 102 Pok Fu Lam Road, Hong Kong. aymwang@hku.hk
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MeSH Terms
Descriptor/Qualifier:
Biological Markers / blood*
Cardiovascular Diseases / blood*,  diagnosis,  etiology
Humans
Kidney Failure, Chronic / blood*,  complications
Natriuretic Peptide, Brain / blood*
Peptide Fragments / blood
Troponin T / blood*
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Peptide Fragments; 0/Troponin T; 0/pro-brain natriuretic peptide (1-76); 114471-18-0/Natriuretic Peptide, Brain

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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