| Use of bisphosphonates to treat severe idiopathic hypercalcaemia in a young Ragdoll cat. | |
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MedLine Citation:
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PMID: 21036642 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 3-year-old Ragdoll cat was referred for investigation of polyuria, polydipsia, vomiting, weight loss and hypercalcaemia. Serum biochemical abnormalities included total and ionised hypercalcaemia and hypophosphataemia. Following clinical investigations a diagnosis of idiopathic hypercalcaemia was made. Because of the severity of the hypercalcaemia and the associated clinical signs, treatment for hypercalcaemia was commenced with pamidronate. Major electrolyte abnormalities were detected but, remarkably, were accompanied by minimal clinical signs. The cat was subsequently treated with oral alendronate and is clinically normal 15 months later. Reports of the use of bisphosphonates in cats are limited and close monitoring of patients is recommended. |
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Authors:
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Joanna L Whitney; Vanessa R D Barrs; Margaret R Wilkinson; Katherine A Briscoe; Julia A Beatty |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-10-30 |
Journal Detail:
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Title: Journal of feline medicine and surgery Volume: 13 ISSN: 1532-2750 ISO Abbreviation: J. Feline Med. Surg. Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-01-31 Completed Date: 2011-04-04 Revised Date: 2011-09-22 |
Medline Journal Info:
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Nlm Unique ID: 100897329 Medline TA: J Feline Med Surg Country: England |
Other Details:
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Languages: eng Pagination: 129-34 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 ISFM and AAFP. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Valentine Charlton Cat Centre, Faculty of Veterinary Science, The University of Sydney, NSW 2006, Australia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Alendronate
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therapeutic use* Animals Bone Density Conservation Agents / therapeutic use* Cat Diseases / drug therapy* Cats Diphosphonates / therapeutic use* Female Follow-Up Studies Hypercalcemia / drug therapy, veterinary* Severity of Illness Index Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Bone Density Conservation Agents; 0/Diphosphonates; 40391-99-9/pamidronate; 66376-36-1/Alendronate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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