Document Detail


Use of biological therapies in rheumatoid arthritis management: a comparison between the main worldwide and brazilian recommendations.
MedLine Citation:
PMID:  21625810     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: Rheumatoid arthritis (RA) is a chronic systemic and progressive inflammatory disorder of the joints, which can result in deformity and functional disability. The diagnosis, treatment, and follow-up of patients with RA vary worldwide. The major societies of rheumatology, as well as governmental agencies in most countries, have tried to establish recommendations addressing diagnosis, treatment, and follow-up of RA. Despite the rapid advance in discovering new drugs, with increasingly efficient therapeutic responses, these recommendations have not been updated accordingly. Thus, efforts should be focused on standardizing the procedures established. Objective: Compare the main international recommendations for treatment of RA with the Brazilian protocols of the Brazilian Society of Rheumatology and Ministry of Health.
METHODS: The protocols of the following entities for treating RA were assessed: Brazilian Ministry of Health, Brazilian Society of Rheumatology, PANLAR/GLADAR, American College of Rheumatology, European League Against Rheumatism (EULAR), and Mexican College of Rheumatology.
RESULTS: Significant differences were identified between the several recommendations, especially regarding the criteria for beginning biological therapies, hierarchic sequence for using available biological drugs, and for suspending or switching them.
CONCLUSIONS: The recommendations for treatment of RA should be more frequently updated. The worldwide standardization of criteria for elaborating recommendations would be of great value to provide similar guidance to rheumatologists in countries and regions throughout the world.
Authors:
Vander Fernandes; Tassia Moraes de Assis; Carolina Carla Queiroz; Patrícia Pires Rey de Figueiredo; Rafaela Untar de Oliveira; Nilzio Antonio da Silva
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Revista brasileira de reumatologia     Volume:  51     ISSN:  1809-4570     ISO Abbreviation:  Rev Bras Reumatol     Publication Date:    2011 May-Jun
Date Detail:
Created Date:  2011-05-31     Completed Date:  2011-10-04     Revised Date:  2012-05-08    
Medline Journal Info:
Nlm Unique ID:  0404256     Medline TA:  Rev Bras Reumatol     Country:  Brazil    
Other Details:
Languages:  eng; por     Pagination:  220-30     Citation Subset:  IM    
Affiliation:
Rheumatology Service of the Hospital Geral Universitario, Universidade de Cuiaba, Brazil. vf@uol.com.br
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MeSH Terms
Descriptor/Qualifier:
Arthritis, Rheumatoid / therapy*
Biological Therapy*
Brazil
Humans
Internationality
Practice Guidelines as Topic*

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