Document Detail

Use of antibiotics to treat bacteriuria of pregnancy in the Nordic countries. Which antibiotics are appropriate to treat bacteriuria of pregnancy?
MedLine Citation:
PMID:  11295409     Owner:  NLM     Status:  MEDLINE    
Bacteriuria in pregnancy with or without clinical symptoms is frequent and increases the risk of pyelonephritis, preterm labour, and low birth weight infants. Commonly used antibiotics such as ampicillin (pivampicillin), amoxicillin, trimethoprim, and sulphonamide are currently associated with a high degree of resistance of the most common pathogen in the urinary tract, Escherichia coli. During the past few decades a number of new and efficient antibacterial antibiotics have been developed. The presumption that a specific drug is safe for both the pregnant woman and the foetus depends on how widely the drug has been used. A recent survey among general practitioners and obstetricians in Denmark, Finland, Norway, and Sweden confirmed that the beta-lactam antibiotic pivmecillinam and nitrofurantoin are the most commonly used agents in the treatment of bacteriuria in pregnancy in the Nordic countries. However, a surprisingly high number of physicians reported that they prescribe sulphonamides during the first two trimesters in spite of resistance of E. coli and possible adverse effects on the foetus.
B Christensen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of antimicrobial agents     Volume:  17     ISSN:  0924-8579     ISO Abbreviation:  Int. J. Antimicrob. Agents     Publication Date:  2001 Apr 
Date Detail:
Created Date:  2001-04-11     Completed Date:  2001-07-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9111860     Medline TA:  Int J Antimicrob Agents     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  283-5     Citation Subset:  IM    
Department of Medical Genetics, Ulleval University Hospital, N-0407 Oslo, Norway.
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MeSH Terms
Anti-Infective Agents, Urinary / therapeutic use*
Bacteriuria / drug therapy*,  epidemiology,  microbiology
Drug Utilization / statistics & numerical data*
Finland / epidemiology
Health Care Surveys
Physician's Practice Patterns / statistics & numerical data
Pregnancy Complications, Infectious / drug therapy*,  epidemiology,  microbiology
Scandinavia / epidemiology
Reg. No./Substance:
0/Anti-Infective Agents, Urinary

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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