Document Detail

Use of the amniotic fluid index combined with estimated fetal weight within 10 days of delivery for prediction of macrosomia at birth.
MedLine Citation:
PMID:  18577666     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to assess the value of combining the sonographically estimated fetal weight (EFW) and amniotic fluid index (AFI) measured within 10 days of term delivery for prediction of macrosomia at birth. METHODS: Prospective sonographic fetal biometric measurements and delivery ward data of a single center, uploaded separately over a 4-year period, were retrospectively linked to yield an unselected sample of nondiabetic pregnancies with live-born term neonates. RESULTS: Of the 1925 pregnancies evaluated, 140 (7.2%) were macrosomic (birth weight > or =4000 g). The AFI was significantly higher in the macrosomic group (P < .001). On receiver operating characteristic curve analysis, the area under the curve was larger for predictions based on the EFW alone than on the AFI. An EFW of 4000 g or higher had a positive predictive value of 46.6% for macrosomia at birth. Use of the previously suggested combined EFW and AFI cutoffs of 3689 g and 119 mm, respectively, yielded a positive predictive value of 30.3%. CONCLUSIONS: Combined use of the EFW and AFI rather than the EFW alone does not improve prediction of macrosomia at birth.
Avi Ben-Haroush; Nir Melamed; Reuven Mashiach; Israel Meizner; Yariv Yogev
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine     Volume:  27     ISSN:  0278-4297     ISO Abbreviation:  J Ultrasound Med     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-06-25     Completed Date:  2008-12-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211547     Medline TA:  J Ultrasound Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1029-32     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Helen Schneider's Hospital for Women, Rabin Medical Center, 49100 Petach Tikva, Israel.
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MeSH Terms
Amniotic Fluid* / ultrasonography
Area Under Curve
Fetal Macrosomia / diagnosis*,  ultrasonography
Fetal Weight*
Gestational Age
Predictive Value of Tests
Pregnancy Outcome
Pregnancy Trimester, Third*
Prospective Studies
ROC Curve
Retrospective Studies
Sensitivity and Specificity
Ultrasonography, Prenatal / methods*

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