Document Detail

Use of amino acids as growth hormone-releasing agents by athletes.
MedLine Citation:
PMID:  12093449     Owner:  NLM     Status:  MEDLINE    
Specific amino acids, such as arginine, lysine and ornithine, can stimulate growth hormone (GH) release when infused intravenously or administered orally. Many individuals consume amino acids before strength training workouts, believing this practice accentuates the exercise-induced GH release, thereby promoting greater gains in muscle mass and strength. The GH response to amino acid administration has a high degree of interindividual variability and may be altered by training status, sex, age, and diet. Although parenteral administration consistently leads to increased circulating GH concentration, oral doses that are great enough to induce significant GH release are likely to cause stomach discomfort and diarrhea. During exercise, intensity is a major determinant of GH release. Although one study showed that arginine infusion can heighten the GH response to exercise, no studies found that pre-exercise oral amino acid supplementation augments GH release. Further, no appropriately conducted scientific studies found that oral supplementation with amino acids, which are capable of inducing GH release, before strength training increases muscle mass and strength to a greater extent than strength training alone. The use of specific amino acids to stimulate GH release by athletes is not recommended.
Joseph A Chromiak; Jose Antonio
Related Documents :
2941269 - Growth hormone and liver mitochondria: time course of effects on respiration and fatty ...
2341389 - Histidine 235 of human sex hormone-binding globulin is the covalent site of attachment ...
1257259 - Studies on the isolation and chemical properties of porcine follicle-stimulating hormone.
6318849 - Inhibition of lipogenesis by vasopressin and angiotensin ii in glycogen-depleted hepato...
7050119 - Structure of chicken hypothalamic luteinizing hormone-releasing hormone. ii. isolation ...
6774799 - Stimulation of lh and fsh secretion following intraventicular injection of cysteic acid...
20349449 - Pretreatment of siam weed stem by several chemical methods for increasing the enzymatic...
947599 - Lipid composition of bile in morbid obesity before and after jejunoileal bypass surgery.
17168669 - Gamma linolenic acid: an antiinflammatory omega-6 fatty acid.
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Nutrition (Burbank, Los Angeles County, Calif.)     Volume:  18     ISSN:  0899-9007     ISO Abbreviation:  Nutrition     Publication Date:    2002 Jul-Aug
Date Detail:
Created Date:  2002-07-02     Completed Date:  2002-08-09     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8802712     Medline TA:  Nutrition     Country:  United States    
Other Details:
Languages:  eng     Pagination:  657-61     Citation Subset:  IM    
Department of Health, Physical Education, Recreation and Sport, Mississippi State University, PO Box 6186, Mississippi State, MS 39762-6186, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Amino Acids / administration & dosage*
Human Growth Hormone / blood,  secretion*
Muscle, Skeletal / anatomy & histology,  drug effects,  physiology
Reg. No./Substance:
0/Amino Acids; 12629-01-5/Human Growth Hormone
Comment In:
Nutrition. 2002 Jul-Aug;18(7-8):683-4   [PMID:  12093457 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Effects of soy protein supplemented with methionine on blood lipids and adiposity of rats.
Next Document:  Antibacterial activity of citrate and acetate.