| Use of tomosynthesis for erosion evaluation in rheumatoid arthritic hands and wrists. | |
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MedLine Citation:
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PMID: 21045184 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To compare tomosynthesis with radiography for the detection of hand and wrist bone erosions in patients with rheumatoid arthritis (RA), using multidetector computed tomography (CT) as the reference method. MATERIALS AND METHODS: The study was approved by the local ethics committee, and written consent was obtained from all patients. From December 2008 to April 2009, 30 consecutive patients with RA were included in this prospective study. They underwent radiography, tomosynthesis, and CT of the most symptomatic hand and wrist on the same day. Two radiologists and one rheumatologist independently read images from the three imaging modalities. RESULTS: A total of 232 erosions were detected with CT, while 199 and 140 erosions, respectively, were detected with tomosynthesis and radiography. More erosions were revealed with CT than with tomosynthesis and radiography (P < .0001); significantly more erosions were shown with tomosynthesis than with radiography (P < .0001). With CT as the reference method for bone erosions, the overall sensitivity, specificity, and accuracy of tomosynthesis were, respectively, 77.6%, 89.9%, and 83.1%. The corresponding values for radiography were 53.9%, 92%, and 70.9%. The sensitivity of each reader increased by roughly 20% with use of tomosynthesis. CONCLUSION: The depiction of bone erosions of the hands and wrists is significantly greater with tomosynthesis than with radiography. |
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Authors:
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Clarissa Canella; Peggy Philippe; Vittorio Pansini; Julia Salleron; René-Marc Flipo; Anne Cotten |
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Publication Detail:
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Type: Journal Article Date: 2010-11-02 |
Journal Detail:
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Title: Radiology Volume: 258 ISSN: 1527-1315 ISO Abbreviation: Radiology Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-24 Completed Date: 2011-02-01 Revised Date: 2011-12-21 |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: United States |
Other Details:
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Languages: eng Pagination: 199-205 Citation Subset: AIM; IM |
Copyright Information:
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© RSNA, 2010 |
Affiliation:
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Department of Musculoskeletal Radiology, Centre de Consultations et d'Imagerie de l'Appareil Locomoteur, Centre Hospitalier Régional Universitaire de Lille, Rue du Professeur Emilie Laine, Lille 59000, France. clacanella@yahoo.com.br |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Arthritis, Rheumatoid / pathology, radiography* Female Hand / pathology, radiography* Humans Male Middle Aged Prospective Studies Radiographic Image Enhancement / methods Radiographic Image Interpretation, Computer-Assisted / methods* Sensitivity and Specificity Statistics, Nonparametric Tomography, X-Ray Computed Wrist / pathology, radiography* Wrist Joint / pathology, radiography* |
| Comments/Corrections | |
Comment In:
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Radiologe. 2011 Nov;51(11):919-20
[PMID:
22015983
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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