Document Detail


The Use of Superoxidized Aqueous Solution versus Saline as a Replacement Solution in the Versajet Lavage System in Chronic Diabetic Foot Ulcers: A Pilot Study.
MedLine Citation:
PMID:  21406695     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Background: The removal of necrotic tissue from chronic wounds is required for wound healing to occur. Hydrodebridement (jet lavage) and superoxidized aqueous solution have been independently used for debriding wounds. We sought to investigate the use of superoxidized aqueous solution with a jet lavage system. Methods: Twenty patients with diabetic foot ulcers were randomly assigned in a 1:1 ratio to receive jet lavage debridement with either superoxidized aqueous solution or standard saline weekly. Results: There was no significant difference between the two treatments in the reduction of bacterial load or wound size in 4 weeks. No adverse reactions were reported for either treatment. Conclusions: The use of superoxidized aqueous solution for jet lavage debridement seemed to be as safe and effective as saline. Future investigations should concentrate on whether superoxidized aqueous solution may reduce the bacterial air contamination associated with hydrodebridement.
Authors:
Frank L Bowling; Ryan T Crews; Eleanna Salgami; David G Armstrong; Andrew J M Boulton
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American Podiatric Medical Association     Volume:  101     ISSN:  1930-8264     ISO Abbreviation:  J Am Podiatr Med Assoc     Publication Date:    2011 Mar-Apr
Date Detail:
Created Date:  2011-03-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8501423     Medline TA:  J Am Podiatr Med Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  124-6     Citation Subset:  IM    
Affiliation:
University Department of Medicine and Diabetes, Manchester Royal Infirmary, Manchester, England.
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