| Use of the SL-IV and the PGL-Tb1 glycolipid antigens in ELISA for the diagnosis of tuberculosis in AIDS patients. | |
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MedLine Citation:
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PMID: 1741916 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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At a predetermined specificity of 100.0%, the sensitivity of ELISA using the PGL-Tb1 and SL-IV antigens and IgG assays was 35.0% for the diagnosis of tuberculosis in AIDS patients (44.1% when tuberculosis was diagnosed before AIDS, 21.7% when AIDS was diagnosed before tuberculosis). Serial assays in sera collected from 11 AIDS patients before tuberculosis was diagnosed indicated that significant antibody titres were detected 10 months before the onset of clinical tuberculosis. Consequently, it was proposed that serodiagnosis using the glycolipid specific antigens should help in deciding on preventive antituberculosis treatment in these patients. |
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Authors:
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H C Berlie; J C Petit; H L David |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Zentralblatt für Bakteriologie : international journal of medical microbiology Volume: 275 ISSN: 0934-8840 ISO Abbreviation: Zentralbl. Bakteriol. Publication Date: 1991 Aug |
Date Detail:
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Created Date: 1992-01-10 Completed Date: 1992-01-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9203851 Medline TA: Zentralbl Bakteriol Country: GERMANY |
Other Details:
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Languages: eng Pagination: 351-7 Citation Subset: IM; X |
Affiliation:
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Laboratoire de Bactériologie-Virologie, Faculté de Médecine, Hôpital Saint Antoine, Paris, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acquired Immunodeficiency Syndrome
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complications* Antibodies, Bacterial / blood Antigens, Bacterial / diagnostic use* Cross Reactions Enzyme-Linked Immunosorbent Assay Glycolipids / diagnostic use*, immunology Humans Mycobacterium avium Complex / immunology Mycobacterium avium-intracellulare Infection / complications Mycobacterium tuberculosis / immunology* Predictive Value of Tests Tuberculosis / complications, diagnosis* |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Bacterial; 0/Antigens, Bacterial; 0/Glycolipids; 0/phenolic glycolipid I, Mycobacterium leprae |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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