Document Detail

The Use of Polyurethane Materials in the Surgery of the Spine: A Review.
MedLine Citation:
PMID:  25151132     Owner:  NLM     Status:  Publisher    
BACKGROUND CONTEXT: The spine contains intervertebral discs and the Interspinous and longitudinal ligaments. These structures are elastomeric or viscoelastic in their mechanical properties and serve to allow and control the movement of the bony elements of the spine. The use of metallic or hard polymeric devices to replace the intervertebral discs and the creation of fusion masses to replace discs and/or vertebral bodies changes the load transfer characteristics of the spine and the range of motion of segments of the spine.
PURPOSE: To survey the literature, regulatory information available on the Web, and industry-reported device development found on the Web to ascertain the usage and outcomes of the use of polyurethane polymers in the design and clinical use of devices for spine surgery.
STUDY DESIGN/SETTING: A systematic review of the available information from all sources concerning the subject materials usage in spinal devices was conducted.
METHODS: A search of the peer-reviewed literature combining spinal surgery with polyurethane or specific types and trade names of medical polyurethanes. Additionally, information available on the Food and Drug Administration Web site and information available for corporate web sites was reviewed in an attempt to identify pertinent information.
RESULTS: The review captured devices that are in testing or have entered clinical practice that utilize elastomeric polyurethane polymers as disc replacements, dynamic stabilization of spinal movement, or motion limitation to relieve nerve root compression and pain, as well as a complete a listing as possible of such devices that have been designed or tested but appear to no longer be pursued. This review summarizes the available information about the uses to which polyurethanes have been tested or are being used in spinal surgery.
CONCLUSIONS: The use of polyurethanes in medicine has expanded as modifications to the stability of the polymers in the physiological environment have been improved. The potential for the use of elastomeric materials to more closely match the mechanical properties of the structures being replaced and to maintain motion between spinal segments appears to hold promise. The published results from the use of the devices which are discussed show early success with these applications of elastomeric materials.
Kenneth R St John
Publication Detail:
Type:  REVIEW     Date:  2014-8-20
Journal Detail:
Title:  The spine journal : official journal of the North American Spine Society     Volume:  -     ISSN:  1878-1632     ISO Abbreviation:  Spine J     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-8-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101130732     Medline TA:  Spine J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Inc. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Baclofen or nNOS inhibitor affect molecular and behavioral alterations evoked by traumatic spinal co...
Next Document:  Toxicity of tetramethylammonium hydroxide to aquatic organisms and its synergistic action with potas...