Document Detail


Use of Leishmania major derived leishmanin for skin test surveys of visceral leishmaniasis in Ethiopia.
MedLine Citation:
PMID:  9145577     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The potential use of Leishmania major derived leishmanin in surveys of visceral leishmaniasis (VL) was examined. The study was conducted in Konso sub-district, southwest Ethiopia involving 51 VL patients, 18 VL contacts, four localised cutaneous leishmaniasis (LCL) cases and 15 healthy controls. Sixty three percent of treated VL patients, 44.4% of VL contacts, all of LCL cases and none of untreated VL patients were positive to the test. Leishmanin skin test (LST) induration sizes of 41 treated VL patients were in the ranges of 0 to 10 mm, with a mean of 4.9 mm. The mean induration size and the positive LST rates in female patients were found to be significantly lower than in males. The major drawback of the antigen in the survey was the relatively smaller and flatter indurations. The relationship of LST to gender and leishmanial disease variant is discussed.
Authors:
A Hailu; N Berhe; A Ali; T Gemetchu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  East African medical journal     Volume:  74     ISSN:  0012-835X     ISO Abbreviation:  East Afr Med J     Publication Date:  1997 Jan 
Date Detail:
Created Date:  1997-05-29     Completed Date:  1997-05-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372766     Medline TA:  East Afr Med J     Country:  KENYA    
Other Details:
Languages:  eng     Pagination:  41-5     Citation Subset:  IM    
Affiliation:
Institute of Pathobiology, Addis Ababa University, Ethiopia.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Animals
Antigens, Protozoan / diagnostic use*
Case-Control Studies
Child
Ethiopia
Female
Humans
Leishmania major / immunology*
Leishmaniasis, Cutaneous / diagnosis
Leishmaniasis, Visceral / diagnosis*
Male
Reproducibility of Results
Sensitivity and Specificity
Sex Characteristics
Skin Tests / methods*
Chemical
Reg. No./Substance:
0/Antigens, Protozoan; 0/leishmanin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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